Olympus Logo
Olympus Logo

Not Available in Your Country
Scientific Articles

We are sorry, but there are no events that match your criteria

New
Synthesis of a selective ratiometric fluorescent probe based on Naphthalimide and its application in human cytochrome P450 1A
Biochemistry & Molecular BiologyApr 27 2018Talanta

Xiuxuan Zhang, Yan Zhou, Xiaofei Gu, Yu Cheng, Manxin Hong, Liqiang Yan, Fulong Ma, Zhengjian Qi

Confocal Laser Scanning Microscope
New
Novel Insights into Staphylococcus aureus Deep Bone Infections: the Involvement of Osteocytes
MicrobiologyApr 24 2018mBio

Dongqing Yang, Asiri R. Wijenayaka, Lucian B. Solomon, Stephen M. Pederson, David M. Findlay, Stephen P. Kidd, Gerald J. Atkins

Confocal Laser Scanning Microscope
New
Bioactivity, Safety, and Efficacy of Amphotericin B Nanomicellar Aerosols Using Sodium Deoxycholate Sulfate as the Lipid Carrier
PharmacologyApr 24 2018AAPS PharmSciTech

Faisal Usman, Ruqaiya Khalil, Zaheer Ul-Haq, Titpawan Nakpheng, and Teerapol Srichana

Confocal Laser Scanning Microscope
New
Jageum-Jung improves 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and suppresses pro-inflammatory chemokine production by inhibiting TNF-α/IFN-γ-induced STAT-1 and NFκB signaling in HaCaT cells
Cancer & ImmunologyApr 14 2018Journal of Ethnopharmacology

Ju-Hye Yang, Hyun Ju Do, Esther Lee, Nam-Hui Yim, Won-Kyung Cho, Kwang-Il Park, Jin Yeul Ma

Confocal Laser Scanning Microscope
New
Micro- and Nano-structured 3D Printed Titanium Implants with Hydroxyapatite Coating for Improved Osseointegration
Biochemistry & Molecular BiologyApr 13 2018Journal of Materials Chemistry B

Qin Jie, Dongqing Yang, Shaheer Maher, Luis lima-marques, Yanmin Zhou, Yujie Chen, Gerald J Atkins and Dusan Losic

Confocal Laser Scanning Microscope
New
A BODIPY disulfonate near-infrared fluorescence-enhanced probe: synthesis, high selectivity to endogenous glutathione and two-photon fluorescent turn-on through thiol-induced SNAr substitution
Biochemistry & Molecular BiologyApr 13 2018Journal of Materials Chemistry B

Xiang Xia, Ying Qian and Baoxing Shen  

Confocal Laser Scanning Microscope
New
Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury
Stem CellsApr 12 2018Cell Stem Cell

Aleksandra Tata, Yoshihiko Kobayashi, Ryan D. Chow, Jasmine Tran, Avani Desai, Abdull J. Massri, Timothy J. McCord, Michael Dee Gunn, Purushothama Rao Tata

Confocal Laser Scanning Microscope
New
TGFβ signaling related genes are involved in hormonal mediation during termite soldier differentiation
Plant & Animal ScienceApr 11 2018PLoS Genetics

Yudai Masuoka, Hajime Yaguchi, Kouhei Toga, Shuji Shigenobu, Kiyoto Maekawa

Research Stereomicroscope System
New
Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs
Stem CellsApr 11 2018Nature Communications

Takashi Ikeda, Takafusa Hikichi, Hisashi Miura, Hirofumi Shibata, Kanae Mitsunaga, Yosuke Yamada, Knut Woltjen, Kei Miyamoto, Ichiro Hiratani, Yasuhiro Yamada, Akitsu Hotta, Takuya Yamamoto, Keisuke Okita & Shinji Masui

Inverted Microscopes
New
Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration
Cell BiologyApr 11 2018Nature Communications

Akihito Harada, Kazumitsu Maehara, Yusuke Ono, Hiroyuki Taguchi, Kiyoshi Yoshioka, Yasuo Kitajima, Yan Xie, Yuko Sato, Takeshi Iwasaki, Jumpei Nogami, Seiji Okada, Tetsuro Komatsu, Yuichiro Semba, Tatsuya Takemoto, Hiroshi Kimura, Hitoshi Kurumizaka & Yasuyuki Ohkawa

Confocal Laser Scanning Microscope
New
SFT-4/Surf4 control ER export of soluble cargo proteins and participate in ER exit site organization
Cell BiologyApr 11 2018The Journal of Cell Biology

Keiko Saegusa, Miyuki Sato, Nobukatsu Morooka, Taichi Hara, Ken Sato

Confocal Laser Scanning Microscope
New
In Vivo Genetic Manipulation of Spermatogonial Stem Cells and Their Microenvironment by Adeno-Associated Viruses
Stem CellsApr 05 2018Stem Cell Reports

Satoshi Watanabe, Mito Kanatsu-Shinohara, Narumi Ogonuki, Shogo Matoba, Atsuo Ogura, Takashi Shinohara

Color and Monochrome Camera
New
Direct Control of SPEECHLESS by PIF4 in the High-Temperature Response of Stomatal Development
Plant & Animal ScienceApr 05 2018Current Biology

On Sun Lau, Zhuojun Song, Zimin Zhou, Kelli A. Davies, Jessica Chang, Xin Yang, Shenqi Wang, Doris Lucyshyn, Irene Hui Zhuang Tay, Philip A. Wigge, Dominique C. Bergmann

Confocal Laser Scanning Microscope
New
A small peptide modulates stomatal control via abscisic acid in long-distance signalling
Plant & Animal ScienceApr 04 2018Nature

Fuminori Takahashi, Takehiro Suzuki, Yuriko Osakabe, Shigeyuki Betsuyaku, Yuki Kondo, Naoshi Dohmae, Hiroo Fukuda, Kazuko Yamaguchi-Shinozaki, Kazuo Shinozaki

Upright Microscopes
New
Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D
Cell BiologyApr 04 2018The Journal of Biological Chemistry

Kou Motani and Hidetaka Kosako

Confocal Laser Scanning Microscope
New
Intrahepatic bile ducts guide establishment of the intrahepatic nerve network in developing and regenerating mouse liver
Developmental BiologyApr 03 2018Development

Naoki Tanimizu, Norihisa Ichinohe, Toshihiro Mitaka

Imaging Software
New
Super-long single-molecule tracking reveals dynamic-anchorage-induced integrin function
Biochemistry & Molecular BiologyApr 02 2018Nature Chemical Biology

Taka A. Tsunoyama, Yusuke Watanabe, Junri Goto, Kazuma Naito, Rinshi S. Kasai, Kenichi G. N. Suzuki, Takahiro K. Fujiwara & Akihiro Kusumi

Inverted Microscopes
New
Identification of an Intra- and Inter-specific Tear Protein Signal in Rodents
NeuroscienceMar 29 2018Current Biology

Mai Tsunoda, Kazunari Miyamichi, Ryo Eguchi, Yasuo Sakuma, Yoshihiro Yoshihara, Takefumi Kikusui, Masayoshi Kuwahara, Kazushige Touhara

Upright Microscopes
Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
Cancer & ImmunologyDevelopmental BiologyMar 26 2018Developmental Cell

Purushothama Rao Tata, Ryan D. Chow, Srinivas Vinod Saladi, Aleksandra Tata, Arvind Konkimalla, Anne Bara, Daniel Montoro, Lida P. Hariri, Angela R. Shih, Mari Mino-Kenudson, Hongmei Mou, Shioko Kimura, Leif W. Ellisen, Jayaraj Rajagopal

Confocal Laser Scanning Microscope
High-Throughput Generation of Durable Droplet Arrays for Single-Cell Encapsulation, Culture, and Monitoring
Biochemistry & Molecular BiologyMar 23 2018Analytical Chemistry

Han Wu, Xinlian Chen, Xinghua Gao, Mengying Zhang, Jinbo Wu, and Weijia Wen

Confocal Laser Scanning Microscope
Parathyroid hormone–like hormone induces epithelial-to-mesenchymal transition of intestinal epithelial cells by activating the transcription factor Runx2
Cell BiologyMar 22 2018American Journal of Pathology

Shuying He, Minmin Xue, Cuiping Liu, Fang Xie, Lan Bai 

Confocal Laser Scanning Microscope
New
Species-Specific Mechanisms of Neuron Subtype Specification Reveal Evolutionary Plasticity of Amniote Brain Development
Developmental BiologyMar 20 2018Cell Reports

Tadashi Nomura, Wataru Yamashita, Hitoshi Gotoh, Katsuhiko Ono

Confocal Laser Scanning Microscope
New
Aortic carboxypeptidase–like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis
Biomedical ResearchMar 19 2018Journal of Clinical Investigation

Toshiaki Teratani, Kengo Tomita, Takahiro Suzuki, Hirotaka Furuhashi, Rie Irie, Makoto Nishikawa, Junji Yamamoto, Toshifumi Hibi, Soichiro Miura, Tohru Minamino, Yuichi Oike, Ryota Hokari, Takanori Kanai

Upright Microscopes
New
The choroid plexus is an important clock component
NeuroscienceMar 14 2018Nature Communications

Jihwan Myung, Christoph Schmal, Sungho Hong, Yoshiaki Tsukizawa, Pia Rose, Yong Zhang, Michael J Holzman, Erik DeSchutter, Hanspeter Herzel, Grigory Bordyugov, Toru Takumi

Bioluminescence Imaging System
New
Excitatory Neuronal Hubs Configure Multisensory Integration of Slow Waves in Association Cortex
NeuroscienceMar 13 2018Cell Reports

Satoshi Kuroki, Takamasa Yoshida, Hidekazu Tsutsui, Mizuho Iwama, Reiko Ando, Takayuki Michikawa, Atsushi Miyawaki, Toshio Ohshima, Shigeyoshi Itohara

Confocal Laser Scanning Microscope
New
Simple mechanosense and response of cilia motion reveal the intrinsic habits of ciliates
Biochemistry & Molecular BiologyMar 12 2018PNAS

Takuya Ohmura, Yukinori Nishigami, Atsushi Taniguchi, Shigenori Nonaka, Junichi Manabe, Takuji Ishikawa, Masatoshi Ichikawa

Confocal Laser Scanning Microscope
New
The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury
Developmental BiologyMar 09 2018The Journal of Biological Chemistry

Hajime Okada, Minami Yamada, Kenji Kamimoto, Cindy Yuet-Yin Kok, Kota Kaneko, Masatsugu Ema, Atsushi Miyajima, and Tohru Itoh

Confocal Laser Scanning Microscope
New
TRPM2 channel aggravates CNS inflammation and cognitive impairment via activation of microglia in chronic cerebral hypoperfusion
NeuroscienceMar 09 2018The Journal of Neuroscience

Jun Miyanohara, Masashi Kakae, Kazuki Nagayasu, Takayuki Nakagawa, Yasuo Mori, Ken Arai, Hisashi Shirakawa and Shuji Kaneko

Confocal Laser Scanning Microscope
Localization of nectin-2α at the boundary between the adjacent somata of the clustered cholinergic neurons and its regulatory role in the subcellular localization of the voltage-gated A-type K+ channel Kv4.2 in the medial habenula
NeuroscienceMar 08 2018Journal of Comparative Neurology

Hajime Shiotani, Muneaki Miyata, Yu Itoh, Shujie Wang, Aika Kaito, Akira Mizoguchi, Miwako Yamasaki, Masahiko Watanabe, Kenji Mandai, Hideki Mochizuki, and Yoshimi Takai

Confocal Laser Scanning Microscope
Actin as a cytoskeletal basis for cell architecture and a protein essential for ecdysis in Prorocentrum minimum (Dinophyceae, Prorocentrales)
Cell BiologyMar 08 2018Phycological Research

Mariia Berdieva, Ilya Pozdnyakov, Olga Matantseva, Nikolay Knyazev, Sergei Skarlato

Confocal Laser Scanning Microscope
New
Nesprins and opposing microtubule motors generate a point force that drives directional nuclear motion in migrating neurons
NeuroscienceMar 08 2018Development

You Kure Wu, Hiroki Umeshima, Junko Kurisu, Mineko Kengaku

Fixed Stage Microscope
New
Neuronal Origin of the Temporal Dynamics of Spontaneous BOLD Activity Correlation
NeuroscienceMar 07 2018Cerebral Cortex

Teppei Matsui  Tomonari Murakami  Kenichi Ohki

Research Macro Zoom Microscope
New
Rab7 knockout unveiled regulated autolysosome maturation induced by glutamine starvation
Cell BiologyMar 07 2018Journal of Cell Science

Yoshihiko Kuchitsu, Yuta Homma, Naonobu Fujita, Mitsunori Fukuda

Multi Photon Laser Scanning Microscope
New
Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis
Cell BiologyMar 06 2018Autophagy

Junji Yamaguchi, Chigure Suzuki, Tomohisa Nanao, Soichirou Kakuta, Kentarou Ozawa, Isei Tanida, Tatsuya Saitoh, Takehiko Sunabori, Masaaki Komatsu, Keiji Tanaka, Shigeki Aoki, Kenji Sakimura & Yasuo Uchiyama

Confocal Laser Scanning Microscope
New
B-1a lymphocytes promote oligodendrogenesis during brain development
NeuroscienceMar 05 2018Nature Neuroscience

Shogo Tanabe & Toshihide Yamashita

Inverted Microscopes
New
A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing
NeuroscienceMar 05 2018Nature Neuroscience

Tatsuya C. Murakami, Tomoyuki Mano, Shu Saikawa, Shuhei A. Horiguchi, Daichi Shigeta, Kousuke Baba, Hiroshi Sekiya, Yoshihiro Shimizu, Kenji F. Tanaka, Hiroshi Kiyonari, Masamitsu Iino, Hideki Mochizuki, Kazuki Tainaka & Hiroki R. Ueda

Research Macro Zoom Microscope
New
Single-molecule analysis of phospholipid scrambling by TMEM16F
Biochemistry & Molecular BiologyMar 05 2018PNAS

Rikiya Watanabe, Takaharu Sakuragi, Hiroyuki Noji and Shigekazu Nagata

Inverted Microscopes
New
Signaling between pancreatic β-cells and macrophages via S100 calcium-binding protein A8 exacerbates β-cell apoptosis and islet inflammation
Biochemistry & Molecular BiologyMar 01 2018The Journal of Biological Chemistry

Hideaki Inoue, Jun Shirakawa, Yu Togashi, Kazuki Tajima, Tomoko Okuyama, Mayu Kyohara, Yui Tanaka, Kazuki Orime, Yoshifumi Saisho, Taketo Yamada, Kimitaka Shibue, Rohit N. Kulkarni, and Yasuo Terauchi

Confocal Laser Scanning Microscope
Secondary Degeneration of Auditory Neurons after Topical Aminoglycoside Administration in a Gerbil Model
NeuroscienceMar 01 2018BioMed Research International

Jae-Hun Lee, Min Young Lee, Phil-Sang Chung, and Jae Yun Jung

Confocal Laser Scanning Microscope
Antiviral activity of transiently expressed mitochondrial antiviral signaling adapter, MAVS orthologue from Asian seabass
Cancer & ImmunologyMar 01 2018Fish and Shellfish Immunology

Rahul Krishnan, Jeena K, Zahoor Mushtaq, K.U. Shyam, Pani Prasad Kurcheti

Confocal Laser Scanning Microscope
Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations
NeuroscienceFeb 28 2018Nature Communications

Gen-ichi Tasaka, Casey J. Guenthner, Amos Shalev, Omri Gilday, Liqun Luo, Adi Mizrahi

Confocal Laser Scanning Microscope
New
Two Parallel Pathways Assign Opposing Odor Valences during Drosophila Memory Formation
Developmental BiologyFeb 27 2018Cell Reports

Daisuke Yamazaki, Makoto Hiroi, Takashi Abe, Kazumichi Shimizu, Maki Minami-Ohtsubo, Yuko Maeyama, Junjiro Horiuchi, Tetsuya Tabata

Multi Photon Laser Scanning Microscope
Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin
Cancer & ImmunologyMicrobiologyFeb 27 2018mBio

Pallab Ghosh, Elizabeth M. Halvorsen, Dustin A. Ammendolia, Nirit Mor-Vaknin, Mary X. D. O’Riordan, John H. Brumell, David M. Markovitz, Darren E. Higgins

Confocal Laser Scanning Microscope
New
Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis
NeuroscienceFeb 26 2018PNAS

Kouki Abe, Hiroko Katsuno, Michinori Toriyama, Kentarou Baba, Tomoyuki Mori, Toshio Hakoshima, Yonehiro Kanemura, Rikiya Watanabe and Naoyuki Inagaki

Inverted Microscopes
T-reg cells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration
Cancer & ImmunologyFeb 23 2018PNAS

Marisella Panduro, Christophe Benoist, and Diane Mathis

Confocal Laser Scanning Microscope
New
EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase
Cancer & ImmunologyFeb 22 2018Nature Communications

Kousuke Kasahara, Hiromasa Aoki, Tohru Kiyono, Shujie Wang, Harumi Kagiwada, Mizuki Yuge, Toshio Tanaka, Yuhei Nishimura, Akira Mizoguchi, Naoki Goshima & Masaki Inagaki

Confocal Laser Scanning Microscope
New
Single cell bioluminescence imaging of deep tissue in freely moving animals
BioimagingFeb 22 2018Science

Satoshi Iwano, Mayu Sugiyama, Hiroshi Hama, Akiya Watakabe, Naomi Hasegawa, Takahiro Kuchimaru, Kazumasa Z. Tanaka, Megumu Takahashi, Yoko Ishida, Junichi Hata, Satoshi Shimozono, Kana Namiki, Takashi Fukano, Masahiro Kiyama, Hideyuki Okano, Shinae Kizaka-Kondoh, Thomas J. McHugh, Tetsuo Yamamori, Hiroyuki Hioki, Shojiro Maki, Atsushi Miyawaki

Bioluminescence Imaging System
Mapping the Mouse Cell Atlas by Microwell-Seq
BioimagingFeb 22 2018Cell

Xiaoping Han, Renying Wang, Yincong Zhou, Lijiang Fei, Huiyu Sun, Shujing Lai, Assieh Saadatpour, Zimin Zhou, Haide Chen, Fang Ye, Daosheng Huang, Yang Xu, Wentao Huang, Mengmeng Jiang, Xinyi Jiang, Jie Mao, Yao Chen, Chenyu Lu, Jin Xie, Qun Fang, Yibin Wang, Rui Yue, Tiefeng Li, He Huang, Stuart H. Orkin, Guo-Cheng Yuan, Ming Chen, Guoji Guo

Confocal Laser Scanning Microscope
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p
Cell BiologyFeb 22 2018Biochemical and Biophysical Research Communications

Qian Xu, Yazhou Cui, Jing Luan, Xiaoyan Zhou, Haiying Li, Jinxiang Han

Confocal Laser Scanning Microscope
Spine Patterning Is Guided by Segmentation of the Notochord Sheath
Developmental BiologyFeb 20 2018Cell Reports

Wopat S, Bagwell J, Sumigray KD, Dickson AL, Huitema LFA, Poss KD, Schulte-Merker S, Bagnat M

Confocal Laser Scanning Microscope
Neuroprotective effect of Annona glabra extract against ethanol-induced apoptotic neurodegeneration in neonatal rats
Developmental BiologyNeuroscienceFeb 18 2018Photochemistry and Photobiology, B: Biology

Hongru Ma, Jianfeng Han, Qinchuan Dong

Confocal Laser Scanning Microscope
High-throughput controllable generation of droplet arrays with low consumption
Materials ScienceFeb 16 2018Applied Surface Science

Yinyin Lin, Zhongsheng Wu, Yibo Gao, Jinbo Wu, Weijia Wen

Confocal Laser Scanning Microscope
Release of Pro-Inflammatory Cytokines from Muscle and Bone Causes Tenocyte Death in a Novel Rotator Cuff In Vitro Explant Culture Model
Biomedical ResearchFeb 15 2018Connective Tissue Research

Brianne K. Connizzo and Alan J. Grodzinsky

Confocal Laser Scanning Microscope
3′-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells
Cancer & ImmunologyPharmacologyFeb 15 2018Theranostics

Yan Sun, Yong-Hao Huang, Feng-Ying Huang, Wen-Li Mei, Quan Liu, Cai-Chun Wang, Ying-Ying Lin, Canhua Huang, Yue-Nan Li, Hao-Fu Dai, Guang-Hong Tan

Confocal Laser Scanning Microscope
New
An evolutionarily conserved NIMA-related kinase directs rhizoid tip growth in the basal land plant Marchantia polymorpha
Developmental BiologyFeb 13 2018Development

Kento Otani, Kimitsune Ishizaki, Ryuichi Nishihama, Shogo Takatani, Takayuki Kohchi, Taku Takahashi, Hiroyasu Motose

Confocal Laser Scanning Microscope
A NIR rhodamine fluorescent chemodosimeter specific for Glutathione: Knoevenagel Condensation, detection of intracellular Glutathione and living cell imaging
Biochemistry & Molecular BiologyFeb 13 2018Journal of Materials Chemistry B

Lu Lu Tong  and   Ying Qian 

Confocal Laser Scanning Microscope
New
Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs
Biochemistry & Molecular BiologyFeb 12 2018Nature Communications

Tetsutaro Hayashi, Haruka Ozaki, Yohei Sasagawa, Mana Umeda, Hiroki Danno & Itoshi Nikaido

Inverted Microscopes
New
Glucocorticoid receptor expression in resident and hematopoietic cells in IgG4-related disease
Biomedical ResearchFeb 12 2018Modern Pathology

Taku Iguchi, Koji Takaori, Akiko Mii, Yuki Sato, Yasunori Suzuki, Hajime Yoshifuji, Hiroshi Seno, Osamu Ogawa, Koichi Omori, Kazuhisa Bessho, Satoru Kondo, Tomokazu Yoshizaki, Hitoshi Nakashima, Takao Saito, Tsuneyo Mimori, Hironori Haga, Mitsuhiro Kawano & Motoko Yanagita

Confocal Laser Scanning Microscope
New
Lupus-like autoimmune disease caused by a lack of Xkr8, a caspase-dependent phospholipid scramblase
Cancer & ImmunologyFeb 12 2018PNAS

Mahiru Kawano and Shigekazu Nagata

Confocal Laser Scanning Microscope
DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation
Cancer & ImmunologyFeb 09 2018Biochemical and Biophysical Research Communications

Takahiro Tomino, Hirotada Tajiri, Takaaki Tatsuguchia,Takahiro Shirai,Kounosuke Oisaki,Shigeki Matsunaga,Fumiyuki Sanematsu,
Daiji Sakata,Tomoharu Yoshizumi, Yoshihiko Maehara,Motomu Kanai,Jean-François Cote,Yoshinori Fukui,Takehito Uruno

Confocal Laser Scanning Microscope
New
ADAM8 Is an Antigen of Tyrosine Kinase Inhibitor-Resistant Chronic Myeloid Leukemia Cells Identified by Patient-Derived Induced Pluripotent Stem Cells
Cancer & ImmunologyFeb 08 2018Stem Cell Reports

Masashi Miyauchi, Junji Koya, Shunya Arai, Sho Yamazaki, Akira Honda, Keisuke Kataoka, Akihide Yoshimi, Kazuki Taoka, Keiki Kumano, Mineo Kurokawa

Confocal Laser Scanning Microscope
New
Hippocampal Ripples Downregulate Synapses
NeuroscienceFeb 08 2018Science

Hiroaki Norimoto, Kenichi Makino, Mengxuan Gao, Yu Shikano, Kazuki Okamoto, Tomoe Ishikawa, Takuya Sasaki, Hiroyuki Hioki, Shigeyoshi Fujisawa, Yuji Ikegaya

Multi Photon Laser Scanning Microscope
New
GTL1 and DF1 regulate root hair growth through transcriptional repression of ROOT HAIR DEFECTIVE 6-LIKE 4 in Arabidopsis
Plant & Animal ScienceFeb 08 2018Development

Michitaro Shibata, Christian Breuer, Ayako Kawamura, Natalie M. Clark, Bart Rymen, Luke Braidwood, Kengo Morohashi, Wolfgang Busch, Philip N. Benfey, Rosangela Sozzani, Keiko Sugimoto

Color and Monochrome Camera
New
Auditory input shapes tonotopic differentiation of Kv1.1 expression in avian cochlear nucleus during late development
NeuroscienceFeb 08 2018The Journal of Neuroscience

Nargis Akter, Ryota Adachi, Akitoshi Kato, Ryota Fukaya and Hiroshi Kuba

Confocal Laser Scanning Microscope
New
MYB and MYBL1 in adenoid cystic carcinoma: diversity in the mode of genomic rearrangement and transcripts
Cancer & ImmunologyFeb 06 2018Modern Pathology

Yuki Togashi, Akito Dobashi, Seiji Sakata, Yukiko Sato, Satoko Baba, Akira Seto, Hiroki Mitani, Kazuyoshi Kawabata & Kengo Takeuchi

Upright Microscopes
Mitochondrial Ferritin is a HIF1a-Inducible Gene that Protects from Hypoxia‐Induced Cell Death in Brain
Biochemistry & Molecular BiologyFeb 05 2018Antioxidants and Redox Signaling

Qiong Wu, Wen-Shuang Wu, Lin Su, Xin Zheng, Wenyue Wu, Paolo Santambrogio, Yujing Gou, Qian Hao, Peina Wang, Yaru Li, Bao-Lu Zhao, Guangjun Nie, Sonia Levi, and Yan-Zhong Chang

Confocal Laser Scanning Microscope
SIP1, a novel SOS2 interaction protein, is involved in salt-stress tolerance in Arabidopsis
Plant & Animal ScienceFeb 04 2018Plant Physiology and Biochemistry

Chuntao Wang, Qian Chen, Nan Xiang, Yuanyuan Liu, Xiangxiang Kong, Yongping Yang, Xiangyang Hu

Confocal Laser Scanning Microscope
New
Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum
NeuroscienceFeb 01 2018Neuron

Naofumi Uesaka, Manabu Abe, Kohtarou Konno, Maya Yamazaki, Kazuto Sakoori, Takaki Watanabe, Tzu-Huei Kao, Takayasu Mikuni, Masahiko Watanabe, Kenji Sakimura and Masanobu Kano

Confocal Laser Scanning Microscope
New
Aberrant astrocyte Ca2+ signals “AxCa signals” exacerbate pathological alterations in an alexander disease model
NeuroscienceJan 31 2018Glia

Kozo Saito, Eiji Shigetomi, Rei Yasuda, Ryuichi Sato, Masakazu Nakano, Kei Tashiro, Kenji F. Tanaka, Kazuhiro Ikenaka, Katsuhiko Mikoshiba, Ikuko Mizuta, Tomokatsu Yoshida, Masanori Nakagawa, Toshiki Mizuno and Schuichi Koizumi

Multi Photon Laser Scanning Microscope
Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes
Cell BiologyJan 30 2018Journal of Molecular Biology

Gustavo Martínez-Noël, Katja Luck, Simone Kühnle, Alice Desbuleux, Patricia Szajner, Jeffrey T. Galligan, Diana Rodriguez, Leon Zheng, Kathleen Boyland, Flavian Leclere, Quan Zhong, David E. Hill, Marc Vidal, Peter M. Howley

Confocal Laser Scanning Microscope
M60-like metalloprotease domain of the Escherichia coli YghJ protein forms amyloid fibrils
Cell BiologyJan 30 2018PLOS One

Mikhail V. Belousov, Stanislav A. Bondarev, Anastasiia O. Kosolapova, Kirill S. Antonets, Anna I. Sulatskaya, Maksim I. Sulatsky, Galina A. Zhouravleva, Irina M. Kuznetsova, Konstantin K. Turoverov, Anton A. Nizhnikov

Confocal Laser Scanning Microscope
New
Synthetic-Molecule/Protein Hybrid Probe with Fluorogenic Switch for Live-Cell Imaging of DNA Methylation
Biochemistry & Molecular BiologyJan 30 2018Journal of The American Chemical Society

Yuichiro Hori, Norimichi Otomura, Ayuko Nishida, Miyako Nishiura, Maho Umeno, Isao Suetake, and Kazuya Kikuchi

Confocal Laser Scanning Microscope
TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer
Cancer & ImmunologyJan 30 2018Oncogene

Ken-ichi Takayama, Takashi Suzuki, Tomoaki Tanaka, Tetsuya Fujimura, Satoru Takahashi, Tomohiko Urano, Kazuhiro Ikeda & Satoshi Inoue

Confocal Laser Scanning Microscope
Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology
NeuroscienceJan 30 2018Nature Communications

Kyota Fujita, Xigui Chen, Hidenori Homma, Kazuhiko Tagawa, Mutsuki Amano, Ayumu Saito, Seiya Imoto, Hiroyasu Akatsu, Yoshio Hashizume, Kozo Kaibuchi, Satoru Miyano & Hitoshi Okazawa

Multi Photon Laser Scanning Microscope
erminal Nerve GnRH3 Neurons Mediate Slow Avoidance of Carbon Dioxide in Larval Zebrafish
NeuroscienceJan 29 2018Cell Reports

Tetsuya Koide, Yoichi Yabuki, Yoshihiro Yoshihara

Multi Photon Laser Scanning Microscope
Identification of a Golgi GPI-N-acetylgalactosamine transferase with tandem transmembrane regions in the catalytic domain
Cell BiologyJan 26 2018Nature Communications

Tetsuya Hirata, Sushil K. Mishra, Shota Nakamura, Kazunobu Saito, Daisuke Motooka, Yoko Takada, Noriyuki Kanzawa, Yoshiko Murakami, Yusuke Maeda, Morihisa Fujita, Yoshiki Yamaguchi & Taroh Kinoshita

Confocal Laser Scanning Microscope
Generative Cell Specification Requires Transcription Factors Evolutionarily Conserved in Land Plants
Plant & Animal ScienceJan 25 2018Current Biology

Shohei Yamaoka, Ryuichi Nishihama, Yoshihiro Yoshitake, Sakiko Ishida, Keisuke Inoue, Misaki Saito, Keitaro Okahashi, Haonan Bao, Hiroyuki Nishida, Katsushi Yamaguchi, Shuji Shigenobu, Kimitsune Ishizaki, Katsuyuki T. Yamato, Takayuki Kohchi

Research Stereomicroscope System
A Tau-Targeted Multifunctional Nanocomposite for Combinational Therapy of Alzheimer’s Disease
PharmacologyJan 24 2018ACS Nano

Qing Chen, Yang Du, Kai Zhang, Zeyu Liang, Jinquan Li, Hao Yu, Rong Ren, Jin Feng, Zhiming Jin, Fangyuan Li, Jihong Sun, Min Zhou, Qinggang He, Xiaolian Sun, Hong Zhang, Mei Tian, and Daishun Ling

Confocal Laser Scanning Microscope
A novel near-infrared styryl-BODIPY fluorescent probe for discrimination of GSH and its application in living cells
Biochemistry & Molecular BiologyJan 23 2018Dyes and Pigments

Chengjun Wang, Xiang Xia, Jirong Luo, Ying Qian

Confocal Laser Scanning Microscope
Vesicular nucleotide transporter mediates ATP release and migration in neutrophils
Jan 23 2018The Journal of Biological Chemistry

Yuika Harada, Yuri Kato, Takaaki Miyaji, Hiroshi Omote, Yoshinori Moriyama, and Miki Hiasa

Dual CCD Color and Monochrome Camera
Synapse Elimination Triggered by BMP4 Exocytosis and Presynaptic BMP Receptor Activation
NeuroscienceJan 23 2018Cell Reports

Takahito Higashi, Shinji Tanaka, Tadatsune Iida, Shigeo Okabe

Confocal Laser Scanning Microscope
Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease
Cancer & ImmunologyJan 23 2018Blood

Tomohiro Yamakawa, Hiroyuki Ohigashi, Daigo Hashimoto, Eiko Hayase, Shuichiro Takahashi, Miyono Miyazaki, Kenjiro Minomi, Masahiro Onozawa, Yoshiro Niitsu and Takanori Teshima

Confocal Laser Scanning Microscope
Induction of porcine reproductive and respiratory syndrome virus (PRRSV)-specific regulatory T lymphocytes (Treg) in the lungs and tracheobronchial lymph nodes of PRRSV-infected pigs
Cancer & ImmunologyMicrobiologyJan 22 2018Veterinary Microbiology

Teerawut Nedumpun, Chaitawat Sirisereewan, Chanoknun Thanmuan, Pong Techapongtada, Rinlapas Puntarotairung, Sarun Naraprasertkul, Roongroje Thanawongnuwech, Sanipa Suradhat

Confocal Laser Scanning Microscope
Control of structure topology and spatial distribution of biomacromolecules in protein ZIF-8 biocomposites
Biochemistry & Molecular BiologyJan 16 2018Chemistry of Materials

Weibin Liang, Raffaele Ricco, Natasha K. Maddigan, Robert P Dickinson, Huoshu Xu, Qiaowei Li, Christopher J. Sumby, Stephen G. Bell, Paolo Falcaro, and Christian J Doonan

Confocal Laser Scanning Microscope
A novel human muscle cell model of Duchenne muscular dystrophy created by CRISPR/Cas9 and evaluation of antisense-mediated exon skipping
PharmacologyJan 16 2018Journal of Human Genetics

Takenori Shimo, Kana Hosoki, Yusuke Nakatsuji, Toshifumi Yokota & Satoshi Obika

Confocal Laser Scanning Microscope
Negative regulation of the Keap1–Nrf2 pathway by a p62/Sqstm1 splicing variant
Cell BiologyJan 16 2018Molecular and Cellular Biology

Shun Kageyama, Tetsuya Saito, Miki Obata, Ryo-hei Koide, Yoshinobu Ichimura, and Masaaki Komatsu

Confocal Laser Scanning Microscope
TNF-α induces Drp1-mediated mitochondrial fragmentation during inflammatory cardiomyocyte injury
Cell BiologyJan 15 2018International Journal of Molecular Medicine

Yue‑Liang Shen, Ying‑Zhou Shi, Gai‑Ge Chen, Lin‑Lin Wang, Ming‑Zhi Zheng, Hong‑Feng Jin, Ying‑Ying Chen

Confocal Laser Scanning Microscope
The protein kinase CK2 substrate Jabba modulates lipid metabolism during Drosophila oogenesis
Developmental BiologyJan 11 2018The Journal of Biological Chemistry

Emily A. McMillan, Sheila M. Longo, Michael D. Smith, Sarah Broskin, Baicheng Lin, Nisha K. Singh, and Todd I. Strochlic

Confocal Laser Scanning Microscope
Nanofiber Membrane supported lung-on-a-chip Microdevice for Anti-cancer Drug Testing
Cancer & ImmunologyJan 09 2018Lab on a Chip

Xingyuan Yang, Kaiyan Li, Xu Zhang, Chang Liu, Bingkun Guo, Weijia Wen, Xinghua Gao

Confocal Laser Scanning Microscope
Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease
Cell BiologyJan 09 2018Cell Reports

Md Fakruddin, Fan-Yan Wei, Takeo Suzuki, Kana Asano, Takashi Kaieda, Akiko Omori, Ryoma Izumi, Atsushi Fujimura, Taku Kaitsuka, Keishi Miyata, Kimi Araki, Yuichi Oike, Luca Scorrano, Tsutomu Suzuki, Kazuhito Tomizawa

Confocal Laser Scanning Microscope
GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose
Biochemistry & Molecular BiologyJan 09 2018Nature Communications

Yusaku Iwasaki, Mio Sendo, Katsuya Dezaki, Tohru Hira, Takehiro Sato, Masanori Nakata, Chayon Goswami, Ryohei Aoki, Takeshi Arai, Parmila Kumari, Masaki Hayakawa, Chiaki Masuda, Takashi Okada, Hiroshi Hara, Daniel J. Drucker, Yuichiro Yamada, Masaaki Tokuda & Toshihiko Yada

Upright Microscopes
Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury
Biomedical ResearchJan 08 2018Nature Medicine

Koshu Okubo, Miho Kurosawa, Mako Kamiya, Yasuteru Urano, Akari Suzuki, Kazuhiko Yamamoto, Koji Hase, Koichiro Homma, Junichi Sasaki, Hiroaki Miyauchi, Tatsuo Hoshino, Matsuhiko Hayashi, Tanya N Mayadas & Junichi Hirahashi

Upright Microscopes
Decreased microglial activation through gut-brain axis by prebiotics, probiotics, or synbiotics effectively restored cognitive function in obese-insulin resistant rats
NeuroscienceJan 07 2018Journal of Neuroinflammation

Titikorn Chunchai, Wannipa Thunapong, Sakawdaurn Yasom, Keerati Wanchai, Sathima Eaimworawuthikul, Gabrielle Metzler, Anusorn Lungkaphin, Anchalee Pongchaidecha, Sasithorn Sirilun, Chaiyavat Chaiyasut, Wasana Pratchayasakul, Parameth Thiennimitr, Nipon Chattipakorn, and Siriporn C. Chattipakorn

Confocal Laser Scanning Microscope
An ultrasensitive electrochemical cytosensor based on the magnetic field assisted binanozymes synergistic catalysis of Fe3O4 nanozyme and reduced graphene oxide/molybdenum disulfide nanozyme
Biochemistry & Molecular BiologyJan 07 2018Sensors and Actuators B

Liang Tian, Jinxu Qi, Kun Qian, Olayinka Oderinde, Yingying Cai, Chen Yao, Wei Song, Yihong Wang

Confocal Laser Scanning Microscope
Role of Purinergic Receptor P2Y1 in spatiotemporal Ca2+ dynamics in astrocytes
NeuroscienceJan 05 2018The Journal of Neuroscience

Eiji Shigetomi, Yukiho J. Hirayama, Kazuhiro Ikenaka, Kenji F. Tanaka and Schuichi Koizumi

Multi Photon Laser Scanning Microscope
Use of a leukocyte-targeted peptide probe as a potential tracer for imaging the tuberculosis granuloma
MicrobiologyJan 04 2018Tuberculosis

Landon W. Locke, Shankaran Kothandaraman, Michael Tweedle, Sarah Chaney, Daniel J. Wozniak, Larry S. Schlesinger

Confocal Laser Scanning Microscope
Physcomitrella MADS-box genes regulate water supply and sperm movement for fertilization
Plant & Animal ScienceJan 03 2018Nature Plants

Shizuka Koshimizu, Rumiko Kofuji, Yuko Sasaki-Sekimoto, Masahide Kikkawa, Mie Shimojima, Hiroyuki Ohta, Shuji Shigenobu, Yukiko Kabeya, Yuji Hiwatashi, Yosuke Tamada, Takashi Murata & Mitsuyasu Hasebe

Research Stereomicroscope System
Parkinson’s disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking
NeuroscienceJan 03 2018Human Molecular Genetics

Shun Yoshida  Takafumi Hasegawa  Mari Suzuki  Naoto Sugeno Junpei Kobayashi  Morio Ueyama  Mitsunori Fukuda  Akemi Ido-Fujibayashi Kiyotoshi Sekiguchi  Michinori Ezura  Akio Kikuchi  Toru Baba  Atsushi Takeda Hideki Mochizuki  Yoshitaka Nagai  Masashi Aoki

Confocal Laser Scanning Microscope
PEGylated chitosan nanoparticles with embedded bismuth sulfide for dual-wavelength fluorescent imaging and photothermal therapy
Cancer & ImmunologyJan 02 2018Carbohydrate Polymers

Ke Wang, Jialang Zhuang, Yubing Liu, Maosheng Xu, Jingyuan Zhuang, Zuanguang Chen, Yen Wei, Yuanqing Zhang

Confocal Laser Scanning Microscope
Optical silencing of body wall muscles induces pumping inhibition in Caenorhabditis elegans
NeuroscienceDec 27 2017PLoS Genetics

Megumi Takahashi, Shin Takagi

Research Macro Zoom Microscope
Facile Deposition of Manganese Dioxide to Albumin Bound Paclitaxel Nanoparticles for Modulation of Hypoxic Tumor Microenvironment to Improve Chemoradiation Therapy
Cancer & ImmunologyDec 22 2017Molecular Pharmaceutics

Lingtong Meng, Yali Cheng, Shaoju Gan, Zhicheng Zhang, Xiaoning Tong, Lei Xu, Xing Jiang, Yishen Zhu, Jinhui Wu, Ahu Yuan, and Yiqiao Hu

Confocal Laser Scanning Microscope
Revealing chiral cell motility by 3D Riesz transform-differential interference contrast microscopy and computational kinematic analysis
NeuroscienceDec 19 2017Nature Communications

Atsushi Tamada & Michihiro Igarashi

Fixed Stage Microscope
Functional characterization of human peptide/histidine transporter 1 in stably transfected MDCK cells
Cell BiologyDec 18 2017Molecular Pharmaceutics

Feifeng Song, Yongjun Hu, Yuqing Wang, David E. Smith, and Huidi Jiang

Confocal Laser Scanning Microscope
The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans
Cell BiologyDec 18 2017Nature Cell Biology

Miyuki Sato, Katsuya Sato, Kotone Tomura, Hidetaka Kosako & Ken Sato

Confocal Laser Scanning Microscope
Identification of Cep169-interacting proteins and the in vivo modification sites of Cep169 via proteomic analysis
Cell BiologyDec 17 2017Biochemical and Biophysical Research Communications

Miyuki Shintomi, Mikihiro Shiratori, Lumi Negishi, Yasuhiko Terada

Confocal Laser Scanning Microscope
APUM24 and nucleolar stress
Plant & Animal ScienceDec 14 2017The Plant Cell

Shugo Maekawa, Tetsuya Ishida, Shuichi Yanagisawa

Dual CCD Color and Monochrome Camera
APP upregulation contributes to retinal ganglion cell degeneration via JNK3
NeuroscienceDec 13 2017Cell Death & Differentiation

Chao Liu, Cheng-Wu Zhang, Yi Zhou, Wan Qing Wong, Liying Corinne Lee, Wei Yi Ong, Sung Ok Yoon, Wanjin Hong, Xin-Yuan Fu, Tuck Wah Soong, Edward H. Koo, Lawrence W. Stanton, Kah-Leong Lim, Zhi-Cheng Xiao, Gavin S. Dawe

Confocal Laser Scanning Microscope
CCL28-Deficient Mice Have Reduced IgA Antibody–Secreting Cells and an Altered Microbiota in the Colon
Cancer & ImmunologyDec 13 2017The Journal of Immunology

Kazuhiko Matsuo, Daisuke Nagakubo, Shinya Yamamoto, Akiko Shigeta, Shuta Tomida, Mitsugu Fujita, Takako Hirata, Ikuo Tsunoda, Takashi Nakayama and Osamu Yoshie

Confocal Laser Scanning Microscope
Synaptic weight set by Munc13-1 supramolecular assemblies
NeuroscienceDec 11 2017Nature Neuroscience

Hirokazu Sakamoto, Tetsuroh Ariyoshi, Naoya Kimpara, Kohtaroh Sugao, Isamu Taiko, Kenji Takikawa, Daisuke Asanuma, Shigeyuki Namiki & Kenzo Hirose

Inverted Microscopes
Salt-inducible kinase 3 regulates the mammalian circadian clock by destabilizing PER2 protein
NeuroscienceDec 11 2017eLife

Naoto Hayasaka Arisa Hirano Yuka Miyoshi Isao T Tokuda Hikari Yoshitane Junichiro Matsuda Yoshitaka Fukada

Bioluminescence Imaging System
Copper (II) oxide nanozyme based electrochemical cytosensor for high sensitive detection of circulating tumor cells in breast cancer
Cancer & ImmunologyDec 08 2017Journal of Electroanalytical Chemistry

Liang Tian, Jinxu Qi, Kun Qian, Olayinka Oderinde, Qinyao Liu, Chen Yao, Wei Song, Yihong Wang

Confocal Laser Scanning Microscope
N-Glycan–dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing
Cell BiologyDec 08 2017The Journal of Cell Biology

Yi-Shi Liu, Xin-Yu Guo, Tetsuya Hirata, Yao Rong, Daisuke Motooka, Toshihiko Kitajima, Yoshiko Murakami, Xiao-Dong Gao, Shota Nakamura, Taroh Kinoshita, Morihisa Fujita

Confocal Laser Scanning Microscope
Mechanosensory-Based Phase Coding of Odor Identity in the Olfactory Bulb
NeuroscienceDec 06 2017Neuron

Ryo Iwata, Hiroshi Kiyonari, Takeshi Imai

Multi Photon Laser Scanning Microscope
Identification of genes regulating GABAergic interneuron maturation
NeuroscienceNov 30 2017Neuroscience Research

Keita Fukumoto, Kota Tamada, Tsuyoshi Toya, Tasuku Nishino, Yuchio Yanagawa, Toru Takumi

Confocal Laser Scanning Microscope
Divergent Connectivity of Homologous Command-like Neurons Mediates Segment-Specific Touch Responses in Drosophila
NeuroscienceNov 30 2017Neuron

Suguru Takagi, Benjamin Thomas Cocanougher, Sawako Niki, Dohjin Miyamoto, Hiroshi Kohsaka, Hokto Kazama, Richard Doty Fetter, James William Truman, Marta Zlatic, Albert Cardona, Akinao Nose

Research Stereomicroscope System
Distinct roles for plasma membrane PtdIns(4)P and PtdIns(4,5)P2 during receptor-mediated endocytosis in yeast
Cell BiologyNov 30 2017Journal of Cell Science

Wataru Yamamoto, Suguru Wada, Makoto Nagano, Kaito Aoshima, Daria Elisabeth Siekhaus, Junko Y. Toshima, Jiro Toshima

Inverted Microscopes
TRPV4 heats up ANO1-dependent exocrine gland fluid secretion
Cell BiologyNov 29 2017The FASEB Journal

Sandra Derouiche, Yasunori Takayama, Masataka Murakami, and Makoto Tominaga

Confocal Laser Scanning Microscope
Lipopolysaccharide structure impacts the entry kinetics of bacterial outer membrane vesicles into host cells
Cancer & ImmunologyNov 29 2017PLOS Pathogens

O'Donoghue EJ, Sirisaengtaksin N, Browning DF, Bielska E, Hadis M, Fernandez-Trillo F, Alderwick L, Jabbari S, Krachler AM.

Confocal Laser Scanning Microscope
CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations
NeuroscienceNov 28 2017eLife

Mihara Shigeki Ohta Kimiko Fukuda Kenji Kurosawa Wado Akamatsu Tsukasa Sanosaka Jun Kohyama Kanehiro Hayashi Kazunori Nakajima Takao Takahashi Joanna Wysocka Kenjiro Kosaki Hideyuki Okano

Research Stereomicroscope System
A Highly Sensitive FRET Biosensor for AMPK Exhibits Heterogeneous AMPK Responses among Cells and Organs
Cell BiologyNov 28 2017Cell Reports

Yumi Konagaya, Kenta Terai, Yusuke Hirao, Kanako Takakura, Masamichi Imajo, Yuji Kamioka, Norio Sasaoka, Akira Kakizuka, Kenta Sumiyama, Tomoichiro Asano, Michiyuki Matsuda

Multi Photon Laser Scanning Microscope
An asymmetric attraction model for the diversity and robustness of cell arrangement in nematodes
Developmental BiologyNov 28 2017Development

Kazunori Yamamoto, Akatsuki Kimura

Inverted Microscopes
MMP-2 Sensitive HA end-conjugated poly(amidoamine) dendrimers via click reaction to enhance drug penetration into solid tumor
Cancer & ImmunologyNov 21 2017Applied Materials & Interfaces

Min Han, Ming-Yi Huang-Fu, Wang-Wei Guo, Ningning Guo, Jiejian Chen, Huina Liu, Zhiqi Xie, Mengting Lin, Qichun Wei, and Jianqing Gao

Confocal Laser Scanning Microscope
RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation
NeuroscienceNov 21 2017eLife

Kei Nakayama Rie Ohashi Yo Shinoda Maya Yamazaki Manabu Abe Akihiro Fujikawa Shuji Shigenobu Akira Futatsugi Masaharu Noda Katsuhiko Mikoshiba Teiichi Furuichi Kenji Sakimura Nobuyuki Shiina

Multi Photon Laser Scanning Microscope
Structural basis for the assembly of the Ragulator-Rag GTPase complex
Biochemistry & Molecular BiologyNov 21 2017Nature Communications

Ryo Yonehara, Shigeyuki Nada, Tomokazu Nakai, Masahiro Nakai, Ayaka Kitamura, Akira Ogawa, Hirokazu Nakatsumi, Keiichi I. Nakayama, Songling Li, Daron M. Standley, Eiki Yamashita, Atsushi Nakagawa & Masato Okada

Confocal Laser Scanning Microscope
Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
Biochemistry & Molecular BiologyNov 21 2017Nature Communications

Hirotake Miyauchi, Satomi Moriyama, Tsukasa Kusakizako, Kaoru Kumazaki, Takanori Nakane, Keitaro Yamashita, Kunio Hirata, Naoshi Dohmae, Tomohiro Nishizawa, Koichi Ito, Takaaki Miyaji, Yoshinori Moriyama, Ryuichiro Ishitani & Osamu Nureki

Automated Fluorescence Microscope
A Mediated BOD Biosensor Based on Immobilized B. Subtilis on Three-Dimensional Porous Graphene-Polypyrrole Composite
BioimagingNov 20 2017Sensors

Jingfang Hu, Yueqi Li, Guowei Gao, and Shanhong Xia

Confocal Laser Scanning Microscope
Both Nodal signalling and stochasticity select for prospective distal visceral endoderm in mouse embryos
Developmental BiologyNov 14 2017Nature Communications

Katsuyoshi Takaoka, Hiromi Nishimura & Hiroshi Hamada

Confocal Laser Scanning Microscope
Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells
Cancer & ImmunologyNov 14 2017Cell Reports

Kayama, Shushi Nagamori, Pornparn Kongpracha, Eiji Umemoto, Ryu Okumura, Takashi Kurakawa, Mari Murakami, Norihisa Mikami, Yasunori Shintani, Satoko Ueno, Ayatoshi Andou, Morihiro Ito, Hideki Tsumura, Koji Yasutomo, Keiichi Ozono, Seiji Takashima, Shimon Sakaguchi, Yoshikatsu Kanai, Kiyoshi Takeda

Upright Microscopes
SATB1 Conditional Knockout Results in Sjögren’s Syndrome in Mice
Cancer & ImmunologyNov 10 2017The Journal of Immunology

Yuriko Tanaka, Takehiko Sotome, Akiko Inoue, Takanori Mukozu, Taku Kuwabara, Tetuo Mikami, Terumi Kowhi-Shigematsu and Motonari Kondo

Automated Fluorescence Microscope
Higher-Order Kidney Organogenesis from Pluripotent Stem Cells
Stem CellsNov 09 2017Cell Stem Cell

Atsuhiro Taguchi, Ryuichi Nishinakamura

Multi Photon Laser Scanning Microscope
Intracellular Protein-Labeling Probes for Multicolor Single-Molecule Imaging of Immune Receptor–Adaptor Molecular Dynamics
Biochemistry & Molecular BiologyNov 09 2017Journal of The American Chemical Society

Ryota Sato, Jun Kozuka, Masahiro Ueda, Reiko Mishima, Yutaro Kumagai, Akimasa Yoshimura, Masafumi Minoshima, Shin Mizukami, and Kazuya Kikuchi

Inverted Microscopes
Distinct Laterality in Forelimb-Movement Representations of Rat Primary and Secondary Motor Cortical Neurons with Intratelencephalic and Pyramidal Tract Projections
NeuroscienceNov 08 2017The Journal of Neuroscience

Shogo Soma, Akiko Saiki, Junichi Yoshida, Alain Ríos, Masanori Kawabata, Yutaka Sakai and Yoshikazu Isomura

Upright Microscopes
Propagating Wave of ERK Activation Orients Collective Cell Migration
Developmental BiologyNov 06 2017Developmental Cell

Kazuhiro Aoki, Yohei Kondo, Honda Naoki, Toru Hiratsuka, Reina E. Itoh, Michiyuki Matsuda

Confocal Laser Scanning Microscope
Area-specific regulation of quiescent neural stem cells by Notch3 in the adult mouse subependymal zone
NeuroscienceStem CellsNov 03 2017The Journal of Neuroscience

Hiroki Kawai, Daichi Kawaguchi, Benjamin D. Kuebrich, Takeo Kitamoto, Masahiro Yamaguchi, Yukiko Gotoh and Shohei Furutachi

Confocal Laser Scanning Microscope
CORTICAL MICROTUBULE DISORDERING1 Is Required for Secondary Cell Wall Patterning in Xylem Vessels
Plant & Animal ScienceNov 03 2017The Plant Cell

Takema Sasaki, Hiroo Fukuda, Yoshihisa Oda

Inverted Microscopes
Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen
Cancer & ImmunologyNov 03 2017The Journal of Immunology

Yasuhiro Mouri, Yoshihiro Ueda, Tomoyoshi Yamano, Minoru Matsumoto, Koichi Tsuneyama, Tatsuo Kinashi and Mitsuru Matsumoto

Multi Photon Laser Scanning Microscope
Nonsteroidal Anti-Inflammatory Drug-Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells
Biochemistry & Molecular BiologyNov 02 2017ACS Infectious Diseases

Aadra P. Bhatt, Dulan B. Gunasekara, Jennifer Speer, Mark I. Reed, Alexis N. Peña, Bentley R. Midkiff, Scott T. Magness, Scott J. Bultman, Nancy L. Allbritton, and Matthew R. Redinbo

Confocal Laser Scanning Microscope
Osteoblast Production by Reserved Progenitor Cells in Zebrafish Bone Regeneration and Maintenance
Developmental BiologyNov 02 2017Developmental Cell

Kazunori Ando, Eri Shibata, Stefan Hans, Michael Brand, Atsushi Kawakami

Confocal Laser Scanning Microscope
Kinetics of Releasable Synaptic Vesicles and Their Plastic Changes at Hippocampal Mossy Fiber Synapses
NeuroscienceNov 02 2017Neuron

Mitsuharu Midorikawa, Takeshi Sakaba

Upright Microscopes
Rufy3 is an adapter protein for small GTPases that activates a Rac guanine nucleotide exchange factor to control neuronal polarity
NeuroscienceOct 31 2017The Journal of Biological Chemistry

Atsuko Honda, Hiroshi Usui, Kenji Sakimura, and Michihiro Igarashi

Upright Microscopes
Genetically-Encoded Tools for Optical Dissection of the Mammalian Cell Cycle
Biochemistry & Molecular BiologyOct 26 2017Molecular Cell

Asako Sakaue-Sawano, Masahiro Yo, Naoki Komatsu, Toru Hiratsuka, Takako Kogure, Tetsushi Hoshida, Naoki Goshima, Michiyuki Matsuda, Hiroyuki Miyoshi, and Atsushi Miyawaki

Confocal Laser Scanning Microscope
R-Spondin1 expands Paneth cells and prevents dysbiosis induced by graft-versus-host disease
Cancer & ImmunologyOct 24 2017The Journal of Experimental Medicine

Eiko Hayase, Daigo Hashimoto, Kiminori Nakamura, Clara Noizat, Reiki Ogasawara, Shuichiro Takahashi, Hiroyuki Ohigashi, Yuki Yokoi, Rina Sugimoto, Satomi Matsuoka, Takahide Ara, Emi Yokoyama, Tomohiro Yamakawa, Ko Ebata, Takeshi Kondo, Rina Hiramine, Tomoyasu Aizawa, Yoshitoshi Ogura, Tetsuya Hayashi, Hiroshi Mori, Ken Kurokawa, Kazuma Tomizuka, Tokiyoshi Ayabe, Takanori Teshima

Color and Monochrome Camera
Motor neurons with limb-innervating character in the cervical spinal cord are sculpted by apoptosis based on the Hox code in chick embryo
Developmental BiologyOct 23 2017Development

Motor neurons with limb-innervating character in the cervical spinal cord are sculpted by apoptosis based on the Hox code in chick embryo

Confocal Laser Scanning Microscope
Autophagy induction under carbon starvation conditions is negatively regulated by carbon catabolite repression
Cell BiologyOct 17 2017The Journal of Biological Chemistry

Atsuhiro Adachi, Michiko Koizumi, and Yoshinori Ohsumi

Inverted Microscopes
Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway
Cell BiologyOct 16 2017PNAS

Takamasa Mizoguchi, Shoko Ikeda, Saori Watanabe, Michiko Sugawara, and Motoyuki Itoh

Inverted Microscopes
Small conductance Ca2+-activated K+ channels induce the firing pause periods during the activation of Drosophila nociceptive neurons
NeuroscienceOct 16 2017eLife

Koun Onodera Shumpei Baba Akira Murakami Tadashi Uemura Tadao Usui

Inverted Microscopes
A long-range cis-regulatory element for class I odorant receptor genes
NeuroscienceOct 12 2017Nature Communications

Tetsuo Iwata, Yoshihito Niimura, Chizuru Kobayashi, Daichi Shirakawa, Hikoyu Suzuki, Takayuki Enomoto, Kazushige Touhara, Yoshihiro Yoshihara & Junji Hirota

Stereo Microscopes
An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling
Developmental BiologyOct 11 2017Gene & Development

Yoshika Hayakawa-Yano, Satoshi Suyama, Masahiro Nogami, Masato Yugami, Ikuko Koya, Takako Furukawa, Li Zhou, Manabu Abe, Kenji Sakimura, Hirohide Takebayashi, Atsushi Nakanishi, Hideyuki Okano, and Masato Yano

Confocal Laser Scanning Microscope
Triple functions nanocomposites of porous silica-CoFe2O4-MWCNTs as carrier for pH-sensitive anti-cancer drugs controlled delivery
Cancer & ImmunologyOct 10 2017Dalton Transactions

Bo Li, Hui-Tao Fan, Xiaojing Xing, Yuhan Yang, Cong-Cong Wang and Dong-Fang Qiu  

Confocal Laser Scanning Microscope
Skin penetration and UV-damage prevention by nanoberries
Cell BiologyOct 09 2017Journal of Cosmetic Dermatology

Paula Bucci,Maria Jimena Prieto, Laura Milla, Maria Natalia Calienni, Luis Martinez, Viviana Rivarola, Silvia Alonso, Jorge Montanari

Confocal Laser Scanning Microscope
The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age
Stem CellsOct 06 2017Nature Communications

Kentaro Hosokawa, Ben D. MacArthur, Yoshiko Matsumoto Ikushima, Hirofumi Toyama, Yoshikazu Masuhiro, Shigemasa Hanazawa, Toshio Suda & Fumio Arai

Confocal Laser Scanning Microscope
3-sulfo-galactosyl dependent adhesion of Escherichia coli HS Multivalent Adhesion Molecule is attenuated by sulfatase activity
Cell BiologyOct 05 2017The Journal of Biological Chemistry

Fitua Al-Saedi, Diana Pereira Vaz, Daniel H Stones, Anne Marie Krachler

Confocal Laser Scanning Microscope
Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells
Stem CellsOct 05 2017Cell Stem Cell

Yoji Kojima, Kotaro Sasaki, Shihori Yokobayashi, Yoshitake Sakai, Tomonori Nakamura, Yukihiro Yabuta, Fumio Nakaki, So Nagaoka, Knut Woltjen, Akitsu Hotta, Takuya Yamamoto, Mitinori Saitou

Confocal Laser Scanning Microscope
Cytoplasmic MTOCs control spindle orientation for asymmetric cell division in plants
Cell BiologyOct 02 2017PNAS

Ken Kosetsu, Takashi Murata, Moé Yamada, Momoko Nishina, Joanna Boruc, Mitsuyasu Hasebe, Daniël Van Damme, and Gohta Goshima

Inverted Microscopes
Functional Segregation and Development of Mouse Higher Visual Areas
NeuroscienceSep 27 2017The Journal of Neuroscience

Tomonari Murakami, Teppei Matsui and Kenichi Ohki

Research Macro Zoom Microscope
Nuclear movement regulated by non-Smad Nodal signaling via JNK is associated with Smad signaling during zebrafish endoderm specification
Developmental BiologySep 25 2017Development

Shunya Hozumi, Shun Aoki, Yutaka Kikuchi

Confocal Laser Scanning Microscope
Optogenetic Activation of the Sensorimotor Cortex Reveals “Local Inhibitory and Global Excitatory” Inputs to the Basal Ganglia
NeuroscienceSep 25 2017eLife

Masashi Kondo Kenta Kobayashi Masamichi Ohkura Junichi Nakai Masanori Matsuzaki

Multi Photon Laser Scanning Microscope
Optogenetic Activation of the Sensorimotor Cortex Reveals “Local Inhibitory and Global Excitatory” Inputs to the Basal Ganglia
NeuroscienceSep 25 2017Cerebral Cortex

Mitsunori Ozaki  Hiromi Sano  Shigeki Sato  Mitsuhiro Ogura Hajime Mushiake  Satomi Chiken  Naoyuki Nakao  Atsushi Nambu

Stereo Microscopes
Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage
Plant & Animal ScienceSep 21 2017Nature Communications

Poyu Chen, Hirotomo Takatsuka, Naoki Takahashi, Rie Kurata, Yoichiro Fukao, Kosuke Kobayashi, Masaki Ito & Masaaki Umeda

Confocal Laser Scanning Microscope
Bone morphogenetic protein and retinoic acid synergistically specify female germ‐cell fate in mice
Biochemistry & Molecular BiologySep 19 2017The EMBO Journal

Hidetaka Miyauchi, Hiroshi Ohta, So Nagaoka, Fumio Nakaki, Kotaro Sasaki, Katsuhiko Hayashi, Yukihiro Yabuta, Tomonori Nakamura, Takuya Yamamoto, Mitinori Saitou

Inverted Microscopes
Dnmt1-dependent Chk1 pathway suppression is protective against neuron division
Developmental BiologySep 19 2017Development

Mio Oshikawa, Kei Okada, Hidenori Tabata, Koh-ichi Nagata, Itsuki Ajioka

Inverted Microscopes
Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis
Biomedical ResearchSep 11 2017Journal of Clinical Investigation

Naoto Koyanagi, Takahiko Imai, Keiko Shindo, Ayuko Sato, Wataru Fujii, Takeshi Ichinohe, Naoki Takemura, Shigeru Kakuta, Satoshi Uematsu, Hiroshi Kiyono, Yuhei Maruzuru, Jun Arii, Akihisa Kato, Yasushi Kawaguchi

Dual CCD Color and Monochrome Camera
Difference in Dachsous Levels between Migrating Cells Coordinates the Direction of Collective Cell Migration
Developmental BiologySep 11 2017Developmental Cell

Masaki Arata, Kaoru Sugimura, Tadashi Uemura

Inverted Microscopes
Rapid transporter regulation prevents substrate flow traffic jams in boron transport
Plant & Animal ScienceSep 05 2017eLife

Naoyuki Sotta Susan Duncan Mayuki Tanaka Takafumi Sato Athanasius FM Marée Toru Fujiwara  Verônica A Grieneisen

Confocal Laser Scanning Microscope
Heterogeneity of mesenchymal and pluripotent stem cell populations grown on nanogrooves and nanopillars
Stem CellsAug 30 2017Journal of Materials Chemistry B

Peng-Yuan Wang, Sheryl Ding, Raymond Wong, Peter Kingshott

Confocal Laser Scanning Microscope
Expression of periostin in breast cancer cells
Cancer & ImmunologyAug 30 2017International Journal of Oncology

Katarzyna Ratajczak-Wielgomas, Jedrzej Grzegrzolka, Aleksandra Piotrowska, Rafal Matkowski, Andrzej Wojnar, Janusz Rys, Maciej Ugorski, Piotr Dziegiel

Confocal Laser Scanning Microscope
Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model
Stem CellsAug 30 2017Nature

Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Hiroaki Magotani, Hirotaka Onoe, Takuya Hayashi, Hiroshi Mizuma, Sayuki Takara, Ryosuke Takahashi, Haruhisa Inoue, Satoshi Morita, Michio Yamamoto, Keisuke Okita, Masato Nakagawa, Malin Parmar & Jun Takahash

Confocal Laser Scanning Microscope
Polo-like kinase Cdc5 regulates Spc72 recruitment to spindle pole body in the methylotrophic yeast Ogataea polymorpha
Biochemistry & Molecular BiologyAug 30 2017eLife

Hiromi Maekawa Annett Neuner Diana Rüthnick Elmar Schiebel Gislene Pereira Yoshinobu Kaneko

Inverted Microscopes
In vitro Generation of Mouse Colon Crypts
Stem CellsAug 29 2017ASC Biomaterials Science & Engineering

Yuli Wang, Dulan Gunasekara, Peter Attayek, Mark Reed, Matthew DiSalvo, Daniel Luke Nguyen, Johanna Dutton, Michael S. Lebhar, Scott Bultman, Christopher E Sims, Scott Magness, and Nancy L Allbritton

Confocal Laser Scanning Microscope
Rab35 GTPase recruits NDP52 to autophagy targets
Biochemistry & Molecular BiologyAug 28 2017The EMBO Journal

Atsuko Minowa‐Nozawa, Takashi Nozawa, Keiko Okamoto‐Furuta, Haruyasu Kohda, Ichiro Nakagawa

Confocal Laser Scanning Microscope
Evidence for ESCRT- and clathrin-dependent microautophagy
Cell BiologyAug 24 2017The Journal of Cell Biology

Masahide Oku, Yuichiro Maeda, Yoko Kagohashi, Takeshi Kondo, Mai Yamada, Toyoshi Fujimoto, Yasuyoshi Sakai

Dual CCD Color and Monochrome Camera
Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development
Biomedical ResearchAug 21 2017PNAS

Yasuhiro Umemura, Nobuya Koike, Munehiro Ohashi, Yoshiki Tsuchiya, Qing Jun Meng, Yoichi Minami, Masayuki Hara, Moe Hisatomi, and Kazuhiro Yagita

Bioluminescence Imaging System
Differing contributions of the first and second pharyngeal arches to tympanic membrane formation in the mouse and chick
Developmental BiologyAug 21 2017Development

Toshiko Furutera, Masaki Takechi, Taro Kitazawa, Junko Takei, Takahiko Yamada, Tri Vu Hoang, Filippo M. Rijli, Hiroki Kurihara, Shigeru Kuratani, Sachiko Iseki

Dual CCD Color and Monochrome Camera
Development of fertile mouse oocytes from mitotic germ cells in vitro
Developmental BiologyAug 10 2017Nature Protocols

Kanako Morohaku, Yuji Hirao & Yayoi Obata

Stereo Microscopes
Neural Circuitry that Evokes Escape Behavior upon Activation of Nociceptive Sensory Neurons in Drosophila Larvae
NeuroscienceAug 10 2017Current Biology

Jiro Yoshino, Rei K. Morikawa, Eri Hasegawa, Kazuo Emoto

Upright Microscopes
A Novel Plasma Membrane-Anchored Protein Regulates Xylem Cell-Wall Deposition through Microtubule-Dependent Lateral Inhibition of Rho GTPase Domains
Plant & Animal ScienceAug 10 2017Current Biology

Yuki Sugiyama, Mayumi Wakazaki, Kiminori Toyooka, Hiroo Fukuda, Yoshihisa Oda

Upright Microscopes
Retrograde BDNF to TrkB signaling promotes synapse elimination in the developing cerebellum
NeuroscienceAug 04 2017Nature Communications

Myeongjeong Choo, Taisuke Miyazaki, Maya Yamazaki, Meiko Kawamura, Takanobu Nakazawa, Jianling Zhang, Asami Tanimura, Naofumi Uesaka, Masahiko Watanabe, Kenji Sakimura & Masanobu Kano

Confocal Laser Scanning Microscope
C/EBPβ is required for survival of Ly6C− monocytes
Cancer & ImmunologyAug 04 2017Blood

Akihiro Tamura, Hideyo Hirai, Asumi Yokota, Naoka Kamio, Atsushi Sato, Tsukimi Shoji, Takahiro Kashiwagi, Yusuke Torikoshi, Yasuo Miura, Daniel G. Tenen and Taira Maekawa

Upright Microscopes
Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis
Cancer & ImmunologyAug 02 2017PNAS

Yuichi Yanagihashi, Katsumori Segawa, Ryota Maeda, Yo-ichi Nabeshima, and Shigekazu Nagata

Confocal Laser Scanning Microscope
The Arabidopsis LAZY1 Family Plays a Key Role in Gravity Signaling within Statocytes and in Branch Angle Control of Roots and Shoots
Plant & Animal ScienceAug 01 2017The Plant Cell

Masatoshi Taniguchi, Masahiko Furutani, Takeshi Nishimura, Moritaka Nakamura, Toyohito Fushita, Kohta Iijima, Kenichiro Baba, Hirokazu Tanaka, Masatsugu Toyota, Masao Tasaka, Miyo Terao Morita

Confocal Laser Scanning Microscope
Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly
Cell BiologyAug 01 2017eLife

Atsuko Shirai Takayuki Kawaguchi Hideaki Shimojo Daisuke Muramatsu Mayumi Ishida-Yonetani Yoshifumi Nishimura Hiroshi Kimura Jun-ichi Nakayama Yoichi Shinkai

Confocal Laser Scanning Microscope
Nrp2 is sufficient to instruct circuit formation of mitral-cells to mediate odour-induced attractive social responses
NeuroscienceJul 21 2017Nature Communications

Kasumi Inokuchi, Fumiaki Imamura, Haruki Takeuchi, Ryang Kim, Hiroyuki Okuno, Hirofumi Nishizumi, Haruhiko Bito, Takefumi Kikusui & Hitoshi Sakano

Upright Microscopes
Origins of Cell-Type-Specific Olfactory Processing in the Drosophila Mushroom Body Circuit
NeuroscienceJul 19 2017Neuron

Kengo Inada, Yoshiko Tsuchimoto, Hokto Kazama

Confocal Laser Scanning Microscope
High expression of ABCG2 induced by EZH2 disruption has pivotal roles in MDS pathogenesis
Cancer & ImmunologyJul 19 2017Leukemia

K C Kawabata, Y Hayashi, D Inoue, H Meguro, H Sakurai, T Fukuyama, Y Tanaka, S Asada, T Fukushima, R Nagase, R Takeda, Y Harada, J Kitaura, S Goyama, H Harada, H Aburatani & T Kitamura

Upright Microscopes
TH2A is phosphorylated at meiotic centromere by Haspin
Reproductive BiologyJul 17 2017Chromosoma

Masashi Hada, Jihye Kim, Erina Inoue, Yuko Fukuda, Hiromitsu Tanaka, Yoshinori Watanabe, Yuki Okada

Confocal Laser Scanning Microscope
Dynamic Organization of Chromatin Domains Revealed by Super-Resolution Live-Cell Imaging
Biochemistry & Molecular BiologyJul 13 2017Molecular Cell

Tadasu Nozaki, Ryosuke Imai, Mai Tanbo, Ryosuke Nagashima, Sachiko Tamura, Tomomi Tani, Yasumasa Joti, Masaru Tomita, Kayo Hibino, Masato T. Kanemaki, Kerstin S. Wendt, Yasushi Okada, Takeharu Nagai, Kazuhiro Maeshima

Confocal Laser Scanning Microscope
Type XVII collagen coordinates proliferation in the interfollicular epidermis
Biomedical ResearchJul 11 2017eLife

Mika Watanabe Ken Natsuga Wataru Nishie Yasuaki Kobayashi Giacomo Donati Shotaro Suzuki Yu Fujimura Tadasuke Tsukiyama Hideyuki Ujiie Satoru Shinkuma Hideki Nakamura Masamoto Murakami Michitaka Ozaki Masaharu Nagayama Fiona M Watt Hiroshi Shimizu

Confocal Laser Scanning Microscope
Defects in dosage compensation impact global gene regulation in the mouse trophoblast
Developmental BiologyJul 06 2017Development

Yuka Sakata, Koji Nagao, Yuko Hoki, Hiroyuki Sasaki, Chikashi Obuse, Takashi Sado

Inverted Microscopes
Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution
Cancer & ImmunologyJul 05 2017Cell Reports

Shimpei I. Kubota, Kei Takahashi, Jun Nishida, Yasuyuki Morishita, Shogo Ehata, Kazuki Tainaka, Kohei Miyazono, Hiroki R. Ueda

Multi Photon Laser Scanning Microscope
Simvastatin induced actin cytoskeleton disassembly in normal and transformed fibroblasts without affecting lipid raft integrity
Cell BiologyJul 03 2017Cell Biology International

Vladislav I. Chubinskiy-Nadezhdin, Yuri A. Negulyaev, and Elena A. Morachevskaya

Confocal Laser Scanning Microscope
Glutamate transporter GLAST controls synaptic wrapping by Bergmann glia and ensures proper wiring of Purkinje cells
NeuroscienceJun 27 2017PNAS

Taisuke Miyazaki, Miwako Yamasaki, Kouichi Hashimoto, Kazuhisa Kohda, Michisuke Yuzaki, Keiko Shimamoto, Kohichi Tanaka, Masanobu Kano, and Masahiko Watanabe

Confocal Laser Scanning Microscope
DNA cytoskeleton for stabilizing artificial cells
Biochemistry & Molecular BiologyJun 26 2017PNAS

Chikako Kurokawa, Kei Fujiwara, Masamune Morita, Ibuki Kawamata, Yui Kawagishi, Atsushi Sakai, Yoshihiro Murayama, Shin-ichiro M. Nomura, Satoshi Murata, Masahiro Takinoue, and Miho Yanagisawa

Confocal Laser Scanning Microscope
Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca2+ permeable AMPA receptor-system xc
NeuroscienceJun 23 2017Toxicology in Vitro

Xin-yue Wang, Yan-li Li, Hai-yun Wang, Min Zhu, Di Guo, Guo-lin Wang, Ying-tang Gao, Zhuo Yang, Tang Li, Chen-yi Yang, Yi-meng Chen

Confocal Laser Scanning Microscope
BACE inhibition-dependent repair of Alzheimer’s pathophysiology
NeuroscienceJun 22 2017PNAS

Aylin D. Keskin, Maja Kekuš, Helmuth Adelsberger, Ulf Neumann, Derya R. Shimshek, Beomjong Song, Benedikt Zott, Tingying Peng, Hans Förstl, Matthias Staufenbiel, Israel Nelken, Bert Sakmann, Arthur Konnerth, and Marc Aurel Busche

Confocal Laser Scanning Microscope
New
A Labeled-Line Neural Circuit for Pheromone-Mediated Sexual Behaviors in Mice
NeuroscienceJun 22 2017Neuron

Kentaro K. Ishii, Takuya Osakada, Hiromi Mori, Nobuhiko Miyasaka, Yoshihiro Yoshihara, Kazunari Miyamichi, Kazushige Touhara

Upright Microscopes
New
Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway
NeuroscienceJun 22 2017Nature Communications

Yosuke M. Morizawa, Yuri Hirayama, Noubuhiko Ohno, Shinsuke Shibata, Eiji Shigetomi, Yang Sui, Junichi Nabekura, Koichi Sato, Fumikazu Okajima, Hirohide Takebayashi, Hideyuki Okano & Schuichi Koizumi

Upright Microscopes
Human iPS‐derived endothelial cells for 3D microphysiological systems
Stem CellsJun 21 2017Tissue Engineering

Yosuke K. Kurokawa, Rose T. Yin, Michael R. Shang, Venktesh S. Shirure, Monica L. Moya, and Steven C. George

Confocal Laser Scanning Microscope
New
High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates
NeuroscienceJun 21 2017Neuron

Kaoru Seiriki, Atsushi Kasai, Takeshi Hashimoto, Wiebke Schulze, Misaki Niu, Shun Yamaguchi, Takanobu Nakazawa, Ken-ichi Inoue, Shiori Uezono, Masahiko Takada, Yuichiro Naka, Hisato Igarashi, Masato Tanuma, James A. Waschek, Yukio Ago, Kenji F. Tanaka, Atsuko Hayata-Takano, Kazuki Nagayasu, Norihito Shintani, Ryota Hashimoto, Yasuto Kunii, Mizuki Hino, Junya Matsumoto, Hirooki Yabe, Takeharu Nagai, Katsumasa Fujita, Toshio Matsuda, Kazuhiro Takuma, Akemichi Baba, Hitoshi Hashimoto

Multiphoton Objectives
New
EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila
Developmental BiologyJun 19 2017Developmental Cell

Michiko Sekiya, Akiko Maruko-Otake, Stephen Hearn, Yasufumi Sakakibara, Naoki Fujisaki, Emiko Suzuki, Kanae Ando, Koichi M. Iijima

Color and Monochrome Camera
New
Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin–N-cadherin pathway after spinal cord injury
Biomedical ResearchJun 19 2017Nature Medicine

Masamitsu Hara, Kazu Kobayakawa, Yasuyuki Ohkawa, Hiromi Kumamaru, Kazuya Yokota, Takeyuki Saito, Ken Kijima, Shingo Yoshizaki, Katsumi Harimaya, Yasuharu Nakashima & Seiji Okada

Upright Microscopes
Inhibition of cyclooxygenase‑2 sensitizes lung cancer cells to radiation‑induced apoptosis
Cancer & ImmunologyJun 15 2017Oncology Letters

ZHI‑QIANG HAN, HONGWEI LIAO, FENG SHI, XIAO‑PING CHEN, HUA‑CHENG HU, MING‑QING TIAN, LI‑HUA WANG and SONGMIN YING

Confocal Laser Scanning Microscope
New
Creation of a Synthetic Ligand for Mitochondrial DNA Sequence Recognition and Promoter-Specific Transcription Suppression
Biochemistry & Molecular BiologyJun 14 2017Journal of The American Chemical Society

Takuya Hidaka, Ganesh N. Pandian, Junichi Taniguchi, Tomohiro Nobeyama, Kaori Hashiya, Toshikazu Bando, and Hiroshi Sugiyama

Confocal Laser Scanning Microscope
New
Bioengineered silkworms with butterfly cytotoxin-modified silk glands produce sericin cocoons with a utility for a new biomaterial
Biochemistry & Molecular BiologyJun 12 2017PNAS

Ryosuke Otsuki, Masafumi Yamamoto, Erika Matsumoto, Shin-ichi Iwamoto, Hideki Sezutsu, Masumi Suzui, Keiko Takaki, Keiji Wakabayashi, Hajime Mori, and Eiji Kotani

Inverted Microscopes
New
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense
Cancer & ImmunologyJun 12 2017Nature Immunology

Miwa Sasai, Naoya Sakaguchi, Ji Su Ma, Shuhei Nakamura, Tsuyoshi Kawabata, Hironori Bando, Youngae Lee, Tatsuya Saitoh, Shizuo Akira, Akiko Iwasaki, Daron M Standley, Tamotsu Yoshimori & Masahiro Yamamoto

Confocal Laser Scanning Microscope
New
Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice
NeuroscienceJun 12 2017Nature Communications

Naoko Morimura, Hiroki Yasuda, Kazuhiko Yamaguchi, Kei-ichi Katayama, Minoru Hatayama, Naoko H. Tomioka, Maya Odagawa, Akiko Kamiya, Yoshimi Iwayama, Motoko Maekawa, Kazuhiko Nakamura, Hideo Matsuzaki, Masatsugu Tsujii, Kazuyuki Yamada, Takeo Yoshikawa & Jun Aruga

Confocal Laser Scanning Microscope
New
Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants
Cell BiologyJun 09 2017Autophagy

Masaaki Uematsu, Taki Nishimura, Yuriko Sakamaki, Hayashi Yamamoto & Noboru Mizushima

Confocal Laser Scanning Microscope
New
NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes
Developmental BiologyJun 06 2017Nature Communications

Zhi Zhou, Hiroshi Kawabe, Atsushi Suzuki, Kaori Shinmyozu & Yumiko Saga

Confocal Laser Scanning Microscope
New
Asymmetric distribution of type IV pili triggered by directional light in unicellular cyanobacteria
Biochemistry & Molecular BiologyJun 05 2017PNAS

Daisuke Nakane and Takayuki Nishizaka

Inverted Microscopes
New
Placental labyrinth formation in mice requires endothelial FLRT2–UNC5B signaling
Developmental BiologyJun 02 2017Development

Ikue Tai-Nagara, Yusuke Yoshikawa, Naoko Numata, Tomofumi Ando, Keisuke Okabe, Yuki Sugiura, Masaki Ieda, Nobuyuki Takakura, Osamu Nakagawa, Bin Zhou, Koji Okabayashi, Makoto Suematsu, Yuko Kitagawa, Martin Bastmeyer, Kohji Sato, Rüdiger Klein, Sutip Navankasattusas, Dean Y. Li, Satoru Yamagishi, Yoshiaki Kubota

Confocal Laser Scanning Microscope
New
Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of Held
NeuroscienceJun 02 2017The Journal of Neuroscience

Kohgaku Eguchi, Zacharie Taoufiq, Oliver Thorn-Seshold, Dirk Trauner, Masato Hasegawa and Tomoyuki Takahashi

Confocal Laser Scanning Microscope
New
A RHO Small GTPase Regulator ABR Secures Mitotic Fidelity in Human Embryonic Stem Cells
Stem CellsJun 01 2017Stem Cell Reports

Masatoshi Ohgushi, Maki Minaguchi, Mototsugu Eiraku, Yoshiki Sasai

Inverted Microscopes
New
Light-driven liquid metal nanotransformers for biomedical theranostics
Biochemistry & Molecular BiologyBiomedical ResearchMay 31 2017Nature Communications

Svetlana A. Chechetka, Yue Yu, Xu Zhen, Manojit Pramanik, Kanyi Pu & Eijiro Miyako

Dual CCD Color and Monochrome Camera
New
Characterization of miR-122-independent propagation of HCV
MicrobiologyMay 29 2017PLOS Pathogens

Chikako Ono, Takasuke Fukuhara, Daisuke Motooka, Shota Nakamura, Daisuke Okuzaki, Satomi Yamamoto, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Kentaro Uemura, Yuzy Fauzyah, Takeshi Kurihara, Takahiro Suda, Akira Nishio, Su Su Hmwe, Toru Okamoto, Tomohide Tatsumi, Tetsuo Takehara, Kazuaki Chayama, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura

Confocal Laser Scanning Microscope
New
Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction
Cancer & ImmunologyMay 26 2017The Journal of Experimental Medicine

Takuma Tsuda, Mikito Takefuji, Nina Wettschureck, Kazuhiko Kotani, Ryota Morimoto, Takahiro Okumura, Harmandeep Kaur, Shunsuke Eguchi, Teruhiro Sakaguchi, Sohta Ishihama, Ryosuke Kikuchi, Kazumasa Unno, Kunihiro Matsushita, Shizukiyo Ishikawa, Stefan Offermanns, Toyoaki Murohara

Upright Microscopes
New
Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide
Biochemistry & Molecular BiologyMay 22 2017Nature Chemistry

Misao Akishiba, Toshihide Takeuchi, Yoshimasa Kawaguchi, Kentarou Sakamoto, Hao-Hsin Yu, Ikuhiko Nakase, Tomoka Takatani-Nakase, Fatemeh Madani, Astrid Gräslund & Shiroh Futaki

Confocal Laser Scanning Microscope
New
Lysophosphatidylinositol-induced activation of the cation channel TRPV2 triggers glucagon-like peptide-1 secretion in enteroendocrine L cells
Biochemistry & Molecular BiologyMay 22 2017The Journal of Biological Chemistry

Kazuki Harada, Tetsuya Kitaguchi, Taichi Kamiya, Kyaw Htet Aung, Kazuaki Nakamura, Kunihiro Ohta, and Takashi Tsuboi

Inverted Microscopes
New
In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome
Biochemistry & Molecular BiologyMay 18 2017Molecular Cell

Hikaru Tsuchiya, Fumiaki Ohtake, Naoko Arai, Ai Kaiho, Sayaka Yasuda, Keiji Tanaka, Yasushi Saeki

Inverted Microscopes
New
Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis
NeuroscienceMay 17 2017Autophagy

Junji Yamaguchi, Chigure Suzuki, Tomohisa Nanao, Soichirou Kakuta, Kentarou Ozawa, Isei Tanida, Tatsuya Saitoh, Takehiko Sunabori, Masaaki Komatsu, Keiji Tanaka, Shigeki Aoki, Kenji Sakimura & Yasuo Uchiyama

Confocal Laser Scanning Microscope
New
Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17
Cell BiologyMay 15 2017Nature Communications

Kohei Arasaki, Yumi Mikami, Stephanie R. Shames, Hiroki Inoue, Yuichi Wakana Mitsuo Tagaya

Microscope Digital Camera
New
A Single Spherical Assembly of Protein Amyloid Fibrils Formed by Laser Trapping
Biochemistry & Molecular BiologyMay 15 2017Angewandte Chemie International Edition

Ken-ichi Yuyama, Mariko Ueda, Satoshi Nagao, Shun Hirota, Teruki Sugiyama, Hiroshi Masuhara

Inverted Microscopes
New
Holliday junction resolvases mediate chloroplast nucleoid segregation
Plant & Animal ScienceMay 12 2017Science

Yusuke Kobayashi, Osami Misumi, Masaki Odahara, Kota Ishibashi, Masafumi Hirono, Kumi Hidaka, Masayuki Endo, Hiroshi Sugiyama, Hiroshi Iwasaki, Tsuneyoshi Kuroiwa, Toshiharu Shikanai, Yoshiki Nishimura

Microscope Digital Camera
New
An Adenosine Receptor for Olfaction in Fish
NeuroscienceMay 11 2017Current Biology

Noriko Wakisaka, Nobuhiko Miyasaka, Tetsuya Koide, Miwa Masuda, Towako Hiraki-Kajiyama, Yoshihiro Yoshihara

Confocal Laser Scanning Microscope
New
Autophagosome formation is initiated at phosphatidylinositol synthase‐enriched ER subdomains
Cell BiologyMay 11 2017The EMBO Journal

Taki Nishimura, Norito Tamura, Nozomu Kono, Yuta Shimanaka, Hiroyuki Arai, Hayashi Yamamoto, Noboru Mizushima

Confocal Laser Scanning Microscope
New
DOK7 gene therapy enhances motor activity and life span in ALS model mice
Biomedical ResearchMay 10 2017EMBO Molecular Medicine

Sadanori Miyoshi, Tohru Tezuka, Sumimasa Arimura, Taro Tomono, Takashi Okada, Yuji Yamanashi

Confocal Laser Scanning Microscope
Multiple roles of afadin in the ultrastructural morphogenesis of mouse hippocampal mossy fiber synapses
NeuroscienceMay 08 2017Journal of Comparative Neurology

Kousyoku Sai, Shujie Wang, Aika Kaito, Takeshi Fujiwara, Tomohiko Maruo, Yu Itoh, Muneaki Miyata, Shotaro Sakakibara, Naoyuki Miyazaki, Kazuyoshi Murata, Yuuki Yamaguchi, Tomohiro Haruta, Hideo Nishioka, Yuki Motojima, Miyuki Komura, Kazushi Kimura, Kenji Mandai, Yoshimi Takai, Akira Mizoguchi

Confocal Laser Scanning Microscope
New
Large Cytoplasm Is Linked to the Error-Prone Nature of Oocytes
Developmental BiologyMay 08 2017Developmental Cell

Hirohisa Kyogoku, Tomoya S. Kitajima

Inverted Microscopes
New
Reconstructing 3D deformation dynamics for curved epithelial sheet morphogenesis from positional data of sparsely-labeled cells
Developmental BiologyMay 02 2017Nature Communications

Yoshihiro Morishita, Ken-ichi Hironaka, Sang-Woo Lee, Takashi Jin Daisuke Ohtsuka

Multi Photon Laser Scanning Microscope
New
Inter-species hormonal control of host root morphology by parasitic plants
Plant & Animal ScienceMay 01 2017PNAS

Thomas Spallek, Charles W. Melnyk, Takanori Wakatake, Jing Zhang, Yuki Sakamoto, Takatoshi Kiba, Satoko Yoshida, Sachihiro Matsunaga, Hitoshi Sakakibara, Ken Shirasu,

Multiphoton Objectives
New
ChIP-seq analysis of genomic binding regions of five major transcription factors in mouse epiblast stem cells that highlights a central role for ZIC2
Developmental BiologyApr 28 2017Development

Kazunari Matsuda, Tomoyuki Mikami, Shinya Oki, Hideaki Iida, Munazah Andrabi, Jeremy M. Boss, Katsushi Yamaguchi, Shuji Shigenobu, Hisato Kondoh

Color and Monochrome Camera
New
Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient model of biliary atresia
Developmental BiologyApr 21 2017Development

Hiroki Higashiyama, Aisa Ozawa, Hiroyuki Sumitomo, Mami Uemura, Ko Fujino, Hitomi Igarashi, Kenya Imaimatsu, Naoki Tsunekawa, Yoshikazu Hirate, Masamichi Kurohmaru, Yukio Saijoh, Masami Kanai-Azuma, Yoshiakira Kanai

Research Stereomicroscope System
New
Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity
Cell BiologyApr 21 2017Cell Death & Differentiation

Kaori Kanemaru, Yoshikazu Nakamura, Kengo Totoki, Takatsugu Fukuyama, Madoka Shoji, Hisae Kaneko, Kanako Shiratori, Atsuko Yoneda, Takafumi Inoue, Yoichiro Iwakura, Kenji Kabashima and Kiyoko Fukami

Inverted Microscopes
New
Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell–cell adhesions in vitro and induces haemorrhage in vivo
Biochemistry & Molecular BiologyApr 20 2017The FEBS Journal

Tadahiko Seo, Taketo Sakon, Shiori Nakazawa, Asuka Nishioka, Kohei Watanabe, Kaori Matsumoto, Mari Akasaka, Narumi Shioi, Hitoshi Sawada, Satohiko Araki

Inverted Microscopes
New
Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes
Cell BiologyApr 17 2017Nature Cell Biology

Shunsuke Kon, Kojiro Ishibashi, Hiroto Katoh, Sho Kitamoto, Takanobu Shirai, Shinya Tanaka, Mihoko Kajita, Susumu Ishikawa, Hajime Yamauchi, Yuta Yako, Tomoko Kamasaki, Tomohiro Matsumoto, Hirotaka Watanabe, Riku Egami, Ayana Sasaki, Atsuko Nishikawa, Ikumi Kameda, Takeshi Maruyama, Rika Narumi, Tomoko Morita, Yoshiteru Sasaki, Ryosuke Enoki, Sato Honma, Hiromi Imamura, Masanobu Oshima, Tomoyoshi Soga, Jun-ichi Miyazaki, Michael R. Duchen, Jin-Min Nam, Yasuhito Onodera, Shingo Yoshioka, Junichi Kikuta, Masaru Ishii, Masamichi Imajo, Eisuke Nishida, Yoichiro Fujioka, Yusuke Ohba, Toshiro Sato Yasuyuki Fujita

Confocal Laser Scanning Microscope
New
Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior
NeuroscienceApr 13 2017The Journal of Experimental Medicine

Yuki Fujita, Koji Masuda, Masashige Bando, Ryuichiro Nakato, Yuki Katou, Takashi Tanaka, Masahiro Nakayama, Keizo Takao, Tsuyoshi Miyakawa, Tatsunori Tanaka, Yukio Ago,Hitoshi Hashimoto, Katsuhiko Shirahige, Toshihide Yamashita

Confocal Laser Scanning Microscope
New
Unusual semi‐extractability as a hallmark of nuclear body‐associated architectural noncoding RNAs
Biochemistry & Molecular BiologyApr 12 2017The EMBO Journal

Takeshi Chujo, Tomohiro Yamazaki, Tetsuya Kawaguchi, Satoshi Kurosaka, Toru Takumi, Shinichi Nakagawa, Tetsuro Hirose

Confocal Laser Scanning Microscope
New
Chemical labelling for visualizing native AMPA receptors in live neurons
NeuroscienceApr 07 2017Nature Communications

Sho Wakayama, Shigeki Kiyonaka, Itaru Arai, Wataru Kakegawa, Shinji Matsuda, Keiji Ibata, Yuri L. Nemoto, Akihiro Kusumi, Michisuke Yuzaki Itaru Hamachi

Confocal Laser Scanning Microscope
New
Compositionally distinct nuclear pore complexes of functionally distinct dimorphic nuclei in ciliate Tetrahymena
Cell BiologyApr 06 2017Journal of Cell Science

Masaaki Iwamoto, Hiroko Osakada, Chie Mori, Yasuhiro Fukuda, Koji Nagao, Chikashi Obuse, Yasushi Hiraoka, Tokuko Haraguchi

Super–Corrected 60X Objective
New
An NADPH Oxidase RBOH Functions in Rice Roots during Lysigenous Aerenchyma Formation under Oxygen-Deficient Conditions
Plant & Animal ScienceMar 28 2017The Plant Cell

Takaki Yamauchi, Miki Yoshioka, Aya Fukazawa, Hitoshi Mori, Naoko K. Nishizawa, Nobuhiro Tsutsumi, Hirofumi Yoshioka, and Mikio Nakazono

Automated Fluorescence Microscope
New
Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance
Developmental BiologyMar 27 2017Developmental Cell

Hiroyuki Nakajima, Kimiko Yamamoto, Sobhika Agarwala, Kenta Terai, Hajime Fukui, Shigetomo Fukuhara, Koji Ando, Takahiro Miyazaki, Yasuhiro Yokota, Etienne Schmelzer, Heinz-Georg Belting, Markus Affolter, Virginie Lecaudey, Naoki Mochizuki

Olympus Super Resolution Microscope
New
Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins
Cell BiologyMar 27 2017PNAS

Katsuhiro Kawaai, Hideaki Ando, Nobuhiko Satoh, Hideomi Yamada, Naoko Ogawa, Matsumi Hirose, Akihiro Mizutani, Benjamin Bonneau, George Seki, and Katsuhiko Mikoshiba

Confocal Laser Scanning Microscope
New
A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF165)
Biochemistry & Molecular BiologyMar 27 2017Nature Chemistry

Hiroyuki Koide, Keiichi Yoshimatsu, Yu Hoshino, Shih-Hui Lee, Ai Okajima, Saki Ariizumi, Yudai Narita, Yusuke Yonamine, Adam C. Weisman, Yuri Nishimura, Naoto Oku, Yoshiko Miura & Kenneth J. Shea

Inverted Microscopes
New
Polar Localization of the NIP5;1 Boric Acid Channel is Maintained by Endocytosis and Facilitates Boron Transport in Arabidopsis Roots
Plant & Animal ScienceMar 24 2017The Plant Cell

Sheliang Wang, Akira Yoshinari, Tomoo Shimada, Ikuko Hara-Nishimura, Namiki Mitani-Ueno, Jian Feng Ma, Satoshi Naito, and Junpei Takano

Research Macro Zoom Microscope
New
Raft-based sphingomyelin interactions revealed by new fluorescent sphingomyelin analogs
Cell BiologyMar 22 2017The Journal of Cell Biology

Masanao Kinoshita, Kenichi G.N. Suzuki, Nobuaki Matsumori, Misa Takada, Hikaru Ano, Kenichi Morigaki, Mitsuhiro Abe, Asami Makino, Toshihide Kobayashi, Koichiro M. Hirosawa, Takahiro K. Fujiwara, Akihiro Kusumi, Michio Murata

Confocal Laser Scanning Microscope
New
Tubulin isotype substitution revealed that isotype composition modulates microtubule dynamics in C. elegans embryos
Cell BiologyMar 16 2017Journal of Cell Science

Yu Honda, Kenta Tsuchiya, Eisuke Sumiyoshi, Nami Haruta, Asako Sugimoto

Silicone Immersion Objectives
New
Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote
Plant & Animal ScienceMar 15 2017Gene & Development

Minako Ueda, Ernst Aichinger, Wen Gong, Edwin Groot, Inge Verstraeten, Lam Dai Vu, Ive De Smet, Tetsuya Higashiyama, Masaaki Umeda, and Thomas Laux

Inverted Microscopes
New
A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking
Developmental BiologyMar 13 2017Developmental Cell

Katsura Minegishi, Masakazu Hashimoto, Rieko Ajima, Katsuyoshi Takaoka, Kyosuke Shinohara, Yayoi Ikawa, Hiromi Nishimura, Andrew P. McMahon, Karl Willert, Yasushi Okada, Hiroshi Sasaki, Dongbo Shi, Toshihiko Fujimori, Toshihisa Ohtsuka, Yasunobu Igarashi, Terry P. Yamaguchi, Akihiko Shimono, Hidetaka Shiratori, Hiroshi Hamada

Confocal Laser Scanning Microscope
New
Extracellular Signals induce Glycoprotein M6a Clustering of Lipid-rafts and associated Signaling Molecules
NeuroscienceMar 08 2017The Journal of Neuroscience

Atsuko Honda, Yasuyuki Ito, Kazuko Takahashi-Niki, Natsuki Matsushita, Motohiro Nozumi, Hidenori Tabata, Kosei Takeuchi and Michihiro Igarashi

Upright Microscopes
New
Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells
Cell BiologyMar 07 2017PNAS

Sayaka Saitoh, Takeshi Maruyama, Yuta Yako, Mihoko Kajita, Yoichiro Fujioka, Yusuke Ohba, Nobuhiro Kasai, Natsu Sugama, Shunsuke Kon, Susumu Ishikawa, Takashi Hayashi, Tomohiro Yamazaki, Masazumi Tada, and Yasuyuki Fujita

Confocal Laser Scanning Microscope
Synthesis of Injectable Alginate Hydrogels with Muscle-Derived Stem Cells for Potential Myocardial Infarction Repair
Stem CellsMar 04 2017Applied Sciences

Rui Fang, Weiming Tian, and Xiongbiao Chen

Confocal Laser Scanning Microscope
New
Coordinated Movement of Vesicles and Actin Bundles during Nerve Growth Revealed by Superresolution Microscopy
Cell BiologyFeb 28 2017Cell Reports

Motohiro Nozumi, Fubito Nakatsu, Kaoru Katoh, Michihiro Igarashi

Confocal Laser Scanning Microscope
New
IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting
Cancer & ImmunologyFeb 24 2017Nature Communications

Hirohisa Kyogoku, Tomoya S. Kitajima

Virtual Microscopes
New
Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma
Cancer & ImmunologyFeb 23 2017The Journal of Experimental Medicine

Takehiro Takahashi, Yoshihide Asano, Koji Sugawara, Takashi Yamashita, Kouki Nakamura, Ryosuke Saigusa, Yohei Ichimura, Tetsuo Toyama, Takashi Taniguchi, Kaname Akamata, Shinji Noda, Ayumi Yoshizaki, Daisuke Tsuruta, Maria Trojanowska, Shinichi Sato

Microscope Digital Camera
New
Allograft inflammatory factor 1 is a regulator of transcytosis in M cells
Cancer & ImmunologyFeb 22 2017Nature Communications

Sari Kishikawa, Shintaro Sato, Satoshi Kaneto, Shigeo Uchino, Shinichi Kohsaka, Seiji Nakamura Hiroshi Kiyono

Confocal Laser Scanning Microscope
New
Distinct intracellular Ca2+ dynamics regulate apical constriction and differentially contribute to neural tube closure
Developmental BiologyFeb 20 2017Development

Makoto Suzuki, Masanao Sato, Hiroshi Koyama, Yusuke Hara, Kentaro Hayashi, Naoko Yasue, Hiromi Imamura, Toshihiko Fujimori, Takeharu Nagai, Robert E. Campbell, Naoto Ueno

Inverted Microscopes
New
Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylation
Cell BiologyFeb 16 2017The Journal of Cell Biology

Taiichi Tsuyama, Asako Tsubouchi,Tadao Usui, Hiromi Imamura, Tadashi Uemura

Research Macro Zoom Microscope
New
Polydom is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling
Biomedical ResearchFeb 08 2017Circulation Research

Nanami Morooka, Sugiko Futaki, Ryoko Sato-Nishiuchi, Masafumi Nishino, Yuta Totani, Chisei Shimono, Itsuko Nakano, Hiroyuki Nakajima, Naoki Mochizuki, Kiyotoshi Sekiguchi

Confocal Laser Scanning Microscope
New
Eccentric position of the germinal vesicle and cortical flow during oocyte maturation specify the animal-vegetal axis of ascidian embryos
Developmental BiologyFeb 07 2017Development

Masumi Tokuhisa, Miyuki Muto, Hiroki Nishida

Automated Fluorescence Microscope
New
Reelin transiently promotes N-cadherin-dependent neuronal adhesion during mouse cortical development
NeuroscienceFeb 06 2017PNAS

Yuki Matsunaga, Mariko Noda, Hideki Murakawa, Kanehiro Hayashi, Arata Nagasaka, Seika Inoue, Takaki Miyata, Takashi Miura, Ken-ichiro Kubo, and Kazunori Nakajima

Confocal Laser Scanning Microscope
New
RAD54 forms DNA repair foci in response to DNA damage in living plant cells
Plant & Animal ScienceFeb 02 2017

Takeshi Hirakawa、Junko Hasegawa、Charles I. White and Sachihiro Matsunaga

Confocal Laser Scanning Microscope
New
Autocrine and paracrine interactions between multiple myeloma cells and bone marrow stromal cells by growth arrest-specific gene 6 crosstalk with interleukin-6
Biochemistry & Molecular BiologyJan 31 2017The Journal of Biological Chemistry

Miki Furukawa, Hiroshi Ohkawara, Kazuei Ogawa, Kazuhiko Ikeda, Koki Ueda, Akiko Shichishima-Nakamura, Emi Ito, Jun-ichi Imai, Yuka Yanagisawa, Reiko Honma, Shinya Watanabe, Satoshi Waguri, Takayuki Ikezoe, and Yasuchika Takeishi

Upright Microscopes
New
NDR1-dependent regulation of kindlin-3 controls high-affinity LFA-1 binding and immune synapse organization
Cell BiologyJan 30 2017Molecular and Cellular Biology

Naoyuki Kondo, Yoshihiro Ueda, Toshiyuki Kita, Madoka Ozawa, Takashi Tomiyama, Kaneki Yasuda, Dae-Sik Lim, and Tatsuo Kinashi

Multi Photon Laser Scanning Microscope
New
A Lin28 homolog reprograms differentiated cells to stem cells in the moss Physcomitrella patens
Stem CellsJan 27 2017Nature Communications

Chen Li, Yusuke Sako, Akihiro Imai, Tomoaki Nishiyama, Kari Thompson, Minoru Kubo, Yuji Hiwatashi, Yukiko Kabeya, Dale Karlson, Shu-Hsing Wu, Masaki Ishikawa, Takashi Murata, Philip N. Benfey, Yoshikatsu Sato, Yosuke Tamada, and Mitsuyasu Hasebe

Research Stereomicroscope System
New
A gustatory neural circuit of Caenorhabditis elegans generates memory-dependent behaviors in Na+ Chemotaxis
NeuroscienceJan 26 2017The Journal of Neuroscience

Lifang Wang, Hirofumi Sato, Yohsuke Satoh, Masahiro Tomioka, Hirofumi Kunitomo, Yuichi Iino

Fixed Stage Microscope
New
Gap junction-mediated signaling from motor neurons regulates motor generation in the central circuits of larval Drosophila
NeuroscienceJan 23 2017The Journal of Neuroscience

Teruyuki Matsunaga, Hiroshi Kohsaka and Akinao Nose

Confocal Laser Scanning Microscope
New
Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis
Developmental BiologyJan 17 2017Cell Reports

Jun Ueda, Akihito Harada, Takashi Urahama, Shinichi Machida, Kazumitsu Maehara, Masashi Hada, Yoshinori Makino, Jumpei Nogami, Naoki Horikoshi, Akihisa Osakabe, Hiroyuki Taguchi, Hiroki Tanaka, Hiroaki Tachiwana, Tatsuma Yao, Minami Yamada, Takashi Iwamoto, Ayako Isotani, Masahito Ikawa, Taro Tachibana, Yuki Okada, Hiroshi Kimura, Yasuyuki Ohkawa, Hitoshi Kurumizaka, Kazuo Yamagata

Confocal Laser Scanning Microscope
New
Basal filopodia and vascular mechanical stress organize fibronectin into pillars bridging the mesoderm-endoderm gap
Developmental BiologyJan 17 2017Development

Yuki Sato, Kei Nagatoshi, Ayumi Hamano, Yuko Imamura, David Huss, Seiichi Uchida, Rusty Lansford

Silicone Immersion Objectives
New
Inhibition of cell polarity establishment in stomatal asymmetric cell division using the chemical compound bubblin
Developmental BiologyJan 13 2017Development

Yumiko Sakai, Shigeo S. Sugano, Takashi Kawase, Makoto Shirakawa, Yu Imai, Yusuke Kawamoto, Hiroshi Sugiyama, Tsuyoshi Nakagawa, Ikuko Hara-Nishimura, Tomoo Shimada

Research Macro Zoom Microscope
New
TBP-like protein (TLP) disrupts the p53-MDM2 interaction and induces long-lasting p53 activation
Biochemistry & Molecular BiologyJan 12 2017The Journal of Biological Chemistry

Ryo Maeda, Hiroyuki Tamashiro, Kazunori Takano, Hiro Takahashi, Hidefumi Suzuki, Shinta Saito, Waka Kojima, Noritaka Adachi, Kiyoe Ura, Takeshi Endo, and Taka-aki Tamura

Confocal Laser Scanning Microscope
New
Environmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans
Biochemistry & Molecular BiologyJan 09 2017Nature Communications

Saya Kishimoto, Masaharu Uno, Emiko Okabe, Masanori Nono Eisuke Nishida

Microscope Digital Camera
New
Intravital Imaging of Neutrophil Recruitment Reveals the Efficacy of FPR1 Blockade in Hepatic Ischemia-Reperfusion Injury
Cancer & ImmunologyJan 06 2017The Journal of Immunology

Masaki Honda, Takayuki Takeichi, Shintaro Hashimoto, Daiki Yoshii, Kaori Isono, Shintaro Hayashida, Yuki Ohya, Hidekazu Yamamoto, Yasuhiko Sugawara and Yukihiro Inomata

Multi Photon Laser Scanning Microscope
New
GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration
Cell BiologyJan 03 2017The Journal of Cell Biology

Shuji Wakatsuki, Shinji Tokunaga, Megumi Shibata, Toshiyuki Araki

Confocal Laser Scanning Microscope
New
Suppression of Dopamine Neurons Mediates Reward
NeuroscienceDec 20 2016PLoS Biology

Nobuhiro Yamagata, Makoto Hiroi, Shu Kondo, Ayako Abe, Hiromu Tanimoto

Confocal Laser Scanning Microscope
New
Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth
NeuroscienceDec 19 2016The Journal of Neuroscience

Kotaro Furusawa, Akiko Asada, Pamela Urrutia, Christian Gonzalez-Billault, Mitsunori Fukuda, and Shin-ichi Hisanaga

Research Macro Zoom Microscope
New
Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish
Developmental BiologyDec 19 2016Development

Ayano Chiba, Haruko Watanabe-Takano, Kenta Terai, Hajime Fukui, Takahiro Miyazaki, Mami Uemura, Hisashi Hashimoto, Masahiko Hibi, Shigetomo Fukuhara, Naoki Mochizuki

Confocal Laser Scanning Microscope
New
Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ
NeuroscienceDec 19 2016Nature Neuroscience

Takashi Matsuda, Takeshi Y Hiyama, Fumio Niimura, Taiji Matsusaka, Akiyoshi Fukamizu, Kenta Kobayashi, Kazuto Kobayashi & Masaharu Noda

Fixed Stage Microscope
New
PIGN prevents protein aggregation in the endoplasmic reticulum independently of its function in the GPI synthesis
Cell BiologyDec 15 2016Journal of Cell Science

Shinji Ihara, Sohei Nakayama, Yoshiko Murakami, Emiko Suzuki, Masayo Asakawa, Taroh Kinoshita, Hitoshi Sawa

Confocal Laser Scanning Microscope
New
Five colour variants of bright luminescent protein for real-time multicolour bioimaging
BioimagingDec 14 2016Nature Communications

Kazushi Suzuki, Taichi Kimura, Hajime Shinoda, Guirong Bai, Matthew J. Daniels, Yoshiyuki Arai, Masahiro Nakano Takeharu Nagai

Bioluminescence Imaging System
New
Optical inactivation of synaptic AMPA receptors erases fear memory
NeuroscienceDec 05 2016Nature

Kiwamu Takemoto, Hiroko Iwanari, Hirobumi Tada, Kumiko Suyama, Akane Sano, Takeharu Nagai, Takao Hamakubo Takuya Takahashi

Upright Microscopes
New
Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal
Developmental BiologyDec 01 2016Gene & Development

Mito Kanatsu-Shinohara, Takashi Tanaka, Narumi Ogonuki, Atsuo Ogura, Hiroko Morimoto, Pei Feng Cheng, Robert N. Eisenman, Andreas Trumpp, and Takashi Shinohara

Confocal Laser Scanning Microscope
New
Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy
Cell BiologyNov 30 2016The Journal of Cell Biology

Shun-ichi Yamashita, Xiulian Jin, Kentaro Furukawa, Maho Hamasaki, Akiko Nezu, Hidenori Otera, Tetsu Saigusa, Tamotsu Yoshimori, Yasuyoshi Sakai, Katsuyoshi Mihara, Tomotake Kanki

Inverted Microscopes
New
Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors
NeuroscienceNov 09 2016The Journal of Neuroscience

Bin Ji, Hiroyuki Kaneko, Takafumi Minamimoto, Haruhisa Inoue, Hiroki Takeuchi, Katsushi Kumata, Ming-Rong Zhang, Ichio Aoki, Chie Seki, Maiko Ono, Masaki Tokunaga, Satoshi Tsukamoto, Koji Tanabe, Ryong-Moon Shin, Takeharu Minamihisamatsu, Seiji Kito, Barry J. Richmond, Tetsuya Suhara and Makoto Higuchi

Inverted Microscopes
New
An Autophagic Flux Probe that Releases an Internal Control
Cell BiologyNov 03 2016Molecular Cell

Takeshi Kaizuka, Hideaki Morishita, Yutaro Hama, Satoshi Tsukamoto, Takahide Matsui, Yuichiro Toyota, Akihiko Kodama, Tomoaki Ishihara, Tohru Mizushima, Noboru Mizushima

Silicone Immersion Objectives
New
Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex
NeuroscienceOct 25 2016PNAS

Hirobumi Tada, Tomoyuki Miyazaki, Kiwamu Takemoto, Kenkichi Takase, Susumu Jitsuki, Waki Nakajima, Mayu Koide, Naoko Yamamoto, Kasane Komiya, Kumiko Suyama, Akane Sano, Akiko Taguchi, and Takuya Takahashi

Multi Photon Laser Scanning Microscope
New
Mixed functional microarchitectures for orientation selectivity in the mouse primary visual cortex
NeuroscienceOct 21 2016Nature Communications

Satoru Kondo, Takashi Yoshida Kenichi Ohki

Dedicated Multi Photon Objectives
The ATG conjugation systems are important for degradation of the inner autophagosomal membrane
Cell BiologyOct 20 2016Science

Kotaro Tsuboyama*First author
Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.

Ikuko Koyama-Honda*Co-first author
Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.

Noboru Mizushima*Last author, Corresponding author
Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.

Confocal Laser Scanning Microscope
New
CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa
Cell BiologyStem CellsOct 19 2016Molecular and Cellular Biology

Samantha A. M. Young, Haruhiko Miyata, Yuhkoh Satouh, Robert John Aitken, Mark A. Baker, Masahito Ikawa

Upright Microscopes
Reconstitution in vitro of the entire cycle of the mouse female germ line
Stem CellsOct 17 2016Nature

Orie Hikabe*First author
Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. 

Katsuhiko Hayashi*Last author, Corresponding author
Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. 

Research Stereomicroscope System
New
Thermodynamic origin of surface melting on ice crystals
Environmental SciencesOct 17 2016PNAS

Ken-ichiro Murata, Harutoshi Asakawa, Ken Nagashima, Yoshinori Furukawa, and Gen Sazaki

Confocal Laser Scanning Microscope
Klf5 regulates muscle differentiation by directly targeting muscle-specific genes in cooperation with MyoD in mice
Biochemistry & Molecular BiologyOct 15 2016eLife

Shinichiro Hayashi*First author
Department of Cellular and Molecular Medicine, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan. 

Yumiko Oishi*Last author, Corresponding author
Department of Cellular and Molecular Medicine, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan. 

Dual CCD Color and Monochrome Camera
Escargot controls the sequential specification of two tracheal tip cell types by suppressing FGF signaling in Drosophila
Developmental BiologyOct 14 2016Development

Guangxia Miao* First author
Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.

Shigeo Hayashi*Last author, Corresponding author
Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.

Confocal Laser Scanning Microscope
Rescue of CAMDI deletion‐induced delayed radial migration and psychiatric behaviors by HDAC6 inhibitor
NeuroscienceOct 13 2016EMBO Reports

Toshifumi Fukuda*First author, Corresponding author
Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.

Shigeru Yanagi*Last author, Corresponding author
Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.

Confocal Laser Scanning Microscope
Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
Stem CellsOct 10 2016Nature

Yuji Shiba*First author, Corresponding author
Laboratory of Molecular Traffic, D1Institute for Biomedical Sciences, Shinshu University, Matsumoto 390-8621, Japan. 

Toshihito Gomibuchi*Co-first author
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.

Uichi Ikeda*Last author, Corresponding author
Department of Cardiovascular Surgery, Shinshu University School of Medicine, Matsumoto 390-8621, Japan. 

Research Stereomicroscope System
The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion
Developmental BiologyOct 06 2016Developmental Cell

Kotaro Sasaki*First author
Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Mitinori Saitou*Last author, Corresponding author
Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Confocal Laser Scanning Microscope
Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1
Stem CellsOct 04 2016Nature Communications

Bumpei Samata* First author
Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

Jun Takahashi*Last author, Corresponding author
Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

Confocal Laser Scanning Microscope
Cancer‐specific mutations in p53 induce the translation of Δ160p53 promoting tumorigenesis
Cancer & ImmunologyOct 04 2016EMBO Reports

Marco M Candeias*First author, Corresponding author
Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.

Michiyuki Matsuda*Last author
Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.

Confocal Laser Scanning Microscope
Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells
Cell BiologyOct 03 2016The Journal of Cell Biology

Masataka Kunii*First author
Department of Molecular and Cellular Biology, Institute for Molecular and Cellular Regulation, Gunma University, Gunma 371-8512, Japan.

Akihiro Harada*Last author, Corresponding author
Department of Molecular and Cellular Biology, Institute for Molecular and Cellular Regulation, Gunma University, Gunma 371-8512, Japan.

Confocal Laser Scanning Microscope
Characterization of novel dystonia musculorum mutant mice: Implications for central nervous system abnormality
NeuroscienceSep 28 2016Neurobiology of Disease

Masao Horie*First author
Division of Neurobiology and Anatomy, Niigata University, Niigata 951-8510, Japan.

Hirohide Takebayashi*Last author, Corresponding author
Division of Neurobiology and Anatomy, Niigata University, Niigata 951-8510, Japan.

Confocal Laser Scanning Microscope
Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways
Cell BiologySep 21 2016Nature Communications

Ippei Kikuchi* First author
Division of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan. 

Masanori Hatakeyama*Last author, Corresponding author
Division of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan. 

Confocal Laser Scanning Microscope
Neural substrate of dynamic Bayesian inference in the cerebral cortex
NeuroscienceSep 19 2016Nature Neuroscience

Akihiro Funamizu*First author
Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University, Tancha, Onna-son, Kunigami, Okinawa, Japan.

Kenji Doya*Last author, Corresponding author
Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University, Tancha, Onna-son, Kunigami, Okinawa, Japan.

Multiphoton Objectives
The Core Molecular Machinery Used for Engulfment of Apoptotic Cells Regulates the JNK Pathway Mediating Axon Regeneration in Caenorhabditis elegans
NeuroscienceSep 14 2016The Journal of Neuroscience

Strahil Iv. Pastuhov*First author
Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan.

Kunihiro Matsumoto*Corresponding author
Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan.

Naoki Hisamoto*Last author, Corresponding author
Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan.

Confocal Laser Scanning Microscope
Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology
NeuroscienceSep 12 2016Human Molecular Genetics

Ying Mao*First author
Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

Hitoshi Okazawa*Last author, Corresponding author
Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

Multi Photon Laser Scanning Microscope
Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose
Biochemistry & Molecular BiologySep 09 2016The Journal of Biological Chemistry

Johan Medina*First author
Institute for Molecular and Cellular Regulation, Gunma University Maebashi 371-8512, Japan.

Itaru Kojima*Last author, Corresponding author
Institute for Molecular and Cellular Regulation, Gunma University Maebashi 371-8512, Japan.

Confocal Laser Scanning Microscope
Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming
Developmental BiologySep 08 2016PLoS Biology

Quan Wu*First author
Division of Mammalian Development, National Institute of Genetics, Mishima, Japan.

Yumiko Saga*Last author, Corresponding author
Division of Mammalian Development, National Institute of Genetics, Mishima, Japan.

Confocal Laser Scanning Microscope
Tumor necrosis factor-alpha-induced protein 8-like 2 (TIPE2) is a novel negative regulator of TAK1 signal
Biochemistry & Molecular BiologySep 06 2016The Journal of Biological Chemistry

Michitaka Oho*First author
From Department of Applied Biological Sciences, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa-city, Kanagawa 252-0880, Japan.

Shigemasa Hanazawa*Last author, Corresponding author
From Department of Applied Biological Sciences, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa-city, Kanagawa 252-0880, Japan.

Confocal Laser Scanning Microscope
Epithelial tumors originate in tumor hotspots, a tissue-intrinsic microenvironment.
Cancer & ImmunologySep 01 2016PLoS Biology

Yoichiro Tamori*First author, Corresponding author
Structural Biology Center, National Institute of Genetics and Department of Genetics, School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), 1111 Yata, Mishima, Japan.

Wu-Min Deng*Last author, Corresponding author
Department of Biological Science, Florida State University, Tallahassee, Florida, United States of America

Confocal Laser Scanning Microscope
Atg9A trafficking through the recycling endosomes is required for autophagosome formation
Cell BiologySep 01 2016Journal of Cell Science

Kenta Imai*First author
Graduate School of Frontier Bioscience, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Takeshi Noda*Corresponding author
Graduate School of Frontier Bioscience, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Tamotsu Yoshimori*Last author, Corresponding author
Graduate School of Frontier Bioscience, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Confocal Laser Scanning Microscope
IKKϵ inhibits PKC to promote Fascin-dependent actin bundling
Developmental BiologyAug 30 2016Development

Tetsuhisa Otani*First author, Corresponding author
Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, Kobe, Hyogo 650-0047, Japan.

Shigeo Hayashi*Last author, Corresponding author
Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, Kobe, Hyogo 650-0047, Japan.

Confocal Laser Scanning Microscope
Multiciliated cell basal bodies align in stereotypical patterns coordinated by the apical cytoskeleton
Cell BiologyAug 29 2016The Journal of Cell Biology

Elisa Herawati*First author
Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.

Daisuke Taniguchi*Co-first author
Department of Physics, School of Science and Technology, Meiji University, Kanagawa 214-8571, Japan.

Shuji Ishihara*Corresponding author
Department of Physics, School of Science and Technology, Meiji University, Kanagawa 214-8571, Japan.

Sachiko Tsukita*Last author, Corresponding author
Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.

Olympus Super Resolution Microscope
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
NeuroscienceAug 24 2016Nature Communications

Seshiru Nakazawa*First author
Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma 371-8512, Japan.

Daisuke Oikawa*Co-first author
Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma 371-8512, Japan.

Hidefumi Ito*Corresponding author
Department of Neurology, Wakayama Medical University, 811-1, Kimiidera, Wakayama, Wakayama 641-8510, Japan.

Osamu Nureki*Corresponding author
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. 

Fuminori Tokunaga*Last author, Corresponding author
Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma 371-8512, Japan.

Confocal Laser Scanning Microscope
A developmental coordinate of pluripotency among mice, monkeys and humans
Stem CellsAug 24 2016Nature

Tomonori Nakamura*First author
Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Mitinori Saitou*Last author, Corresponding author
Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Confocal Laser Scanning Microscope
ARHGEF10 directs the localization of Rab8 to Rab6-positive executive vesicles
NeuroscienceAug 22 2016Journal of Cell Science

Satoshi Shibata*First author, Corresponding author
From Group of Neurobiology, Division of Health Sciences, Graduate School of Medicine, Osaka University, Osaka, 565-0871 Japan.

Shinobu Inagaki*Last author, Corresponding author
From Group of Neurobiology, Division of Health Sciences, Graduate School of Medicine, Osaka University, Osaka, 565-0871 Japan.

Confocal Laser Scanning Microscope
New
The RNA Binding Protein Mex-3B Is Required for IL-33 Induction in the Development of Allergic Airway Inflammation
Cancer & ImmunologyAug 18 2016Cell Reports

Yusuke Yamazum*First author

Laboratory of Molecular and Genetic Information, Institute for Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.

Tetsu Akiyama*Last author, Corresponding author

Laboratory of Molecular and Genetic Information, Institute for Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.

Imaging Software
New
Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
Biochemistry & Molecular BiologyAug 17 2016Nature Communications

Takashi Ohtsuki*First author, Corresponding author

Department of Biomedical Engineering, Okayama University, 3-1-1 Tsushimanaka, Okayama 700-8530, Japan.

Kazunori Watanabe*Last author

Department of Biomedical Engineering, Okayama University, 3-1-1 Tsushimanaka, Okayama 700-8530, Japan.

Confocal Laser Scanning Microscope
New
Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry
Biochemistry & Molecular BiologyAug 15 2016Nature Chemical Biology

Kei Yamaura*First author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, Japan.

Shigeki Kiyonaka*Corresponding author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, Japan.

Itaru Hamachi*Last author, Corresponding author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, Japan.

Confocal Laser Scanning Microscope
New
RpA1 ameliorates symptoms of mutant Ataxin-1 knock-in mice and enhances DNA damage repair
NeuroscienceAug 11 2016Human Molecular Genetics

Juliana Bosso Taniguchi*First author

Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan

Hitoshi Okazawa*Last author, Corresponding author

Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan

Confocal Laser Scanning Microscope
Quiescent center initiation in the Arabidopsis lateral root primordia is dependent on the SCARECROW transcription factor
Plant & Animal ScienceAug 10 2016Development

Kotaro Tsuboyama*First author, Corresponding author
Department of Biology, Graduate School of Science, Kobe University, Kobe 657-8501, Japan.

Soazig Guyomarc'h*Last author, Corresponding author
5Université de Montpellier, Unité Mixte de Recherche (UMR) Diversité Adaptation et Développement des plantes (DIADE), 34394 Montpellier Cedex 5, France.

Confocal Laser Scanning Microscope
New
Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity
Cancer & ImmunologyAug 09 2016Immunity

Tatsuma Ban*First author

Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.

Go R. Sato*Co-first author

Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.

Tomohiko Tamura*Last author, Corresponding author

Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.

Confocal Laser Scanning Microscope
New
A Subtype of Olfactory Bulb Interneurons Is Required for Odor Detection and Discrimination Behaviors
NeuroscienceAug 03 2016The Journal of Neuroscience

Hiroo Takahashi*First author

Laboratory for Molecular Biology of Neural System, Advanced Medical Research Center, Nara Medical University School of Medicine, Kashihara, Nara 634-8521, Japan.

Yoichi Ogawa*Co-first author

Department of Physiology I, Nara Medical University School of Medicine, Kashihara, Nara 634-8521, Japan.

Akio Tsuboi*Last author, Corresponding author

Laboratory for Molecular Biology of Neural System, Advanced Medical Research Center, Nara Medical University School of Medicine, Kashihara, Nara 634-8521, Japan.

Confocal Laser Scanning Microscope
New
In vivo FRET imaging of tumor endothelial cells highlights a role of low PKA activity in vascular hyperpermeability
Cancer & ImmunologyAug 03 2016Cancer Research

Fumio Yamauchi*First author

Department of Pathology and Biology of Diseases, Kyoto University - Graduate School of Medicine, Yoshida-Konoe-cho, Sakyo-ku, Kyoto, Kyoto, 606-8501, Japan.

Michiyuki Matsuda*Last author, Corresponding author

Department of Pathology and Biology of Diseases, Kyoto University - Graduate School of Medicine, Yoshida-Konoe-cho, Sakyo-ku, Kyoto, Kyoto, 606-8501, Japan.

Multi Photon Laser Scanning Microscope
New
Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling
Developmental BiologyJul 19 2016eLife

Kenji Kamimoto*First author

Laboratory of Cell Growth and Differentiation, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan

Tohru Itoh*Last author, Corresponding author

Laboratory of Cell Growth and Differentiation, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan

Silicone Immersion Objectives
New
Liver Progenitors Isolated from Adult Healthy Mouse Liver Efficiently Differentiate to Functional Hepatocytes In Vitro and Repopulate Liver Tissue
Stem CellsJul 13 2016Stem Cells

Naoki Tanimizu*First author

Department of Tissue Development and Regeneration, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Toshihiro Mitaka*Last author, Corresponding author

Department of Tissue Development and Regeneration, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Imaging Software
The intrinsically disordered protein Atg13 mediates supramolecular assembly of autophagy initiation complexes
Cell BiologyJul 11 2016Developmental Cell

Hayashi Yamamoto* First author

Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan

Yuko Fujioka*Co-first author

Institute of Microbial Chemistry (BIKAKEN), Tokyo 141-0021, Japan

Sho W. Suzuki*Co-first author

Frontier Research Center, Tokyo Institute of Technology, Yokohama 226-8503, Japan

Nobuo N. Noda*Corresponding author

Institute of Microbial Chemistry (BIKAKEN), Tokyo 141-0021, Japan

Yoshinori Ohsumi*Last author, Corresponding author

Frontier Research Center, Tokyo Institute of Technology, Yokohama 226-8503, Japan

TIRF Objectives
New
Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator
Cancer & ImmunologyJul 11 2016The Journal of Experimental Medicine

Nobuko Akiyama*First author

Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan.

Taishin Akiyama*Last author, Corresponding author

Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan.

Confocal Laser Scanning Microscope
A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling
NeuroscienceJul 05 2016Molecular Psychiatry

M Fujitani*First author, Corresponding author

Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, Suita, Japan

T Yamashita*Last author, Corresponding author

Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, Suita, Japan

Confocal Laser Scanning Microscope
The Sam68 nuclear body is composed of two RNase-sensitive substructures joined by the adaptor HNRNPL
Cancer & ImmunologyJul 04 2016The Journal of Cell Biology

Taro Mannen*First author

Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan

Tetsuro Hirose*Last author, Corresponding author

Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan

Confocal Laser Scanning Microscope
Developmental Switch in Spike Timing-Dependent Plasticity and Cannabinoid-Dependent Reorganization of the Thalamocortical Projection in the Barrel Cortex
NeuroscienceJun 29 2016The Journal of Neuroscience

Chiaki Itami*First author

Department of Physiology, Faculty of Medicine, Saitama Medical University, Moroyama, Saitama 350-0495, Japan

Fumitaka Kimura*Last author, Corresponding author

Department of Molecular Neuroscience, Osaka University Graduate School of Medicine, Suita 565-0871, Japan 

Confocal Laser Scanning Microscope
Memory of cell shape biases stochastic fate decision-making despite mitotic rounding
Cell BiologyJun 28 2016Nature Communications

Takashi Akanuma*First author, Corresponding author

The Thomas N. Sato BioMEC-X Laboratories, Advanced Telecommunications Research Institute International (ATR), Hikaridai 2-2-2, Kyoto 619-0288, Japan

Thomas N. Sato*Last author, Corresponding author

The Thomas N. Sato BioMEC-X Laboratories, Advanced Telecommunications Research Institute International (ATR), Hikaridai 2-2-2, Kyoto 619-0288, Japan

Multi Photon Laser Scanning Microscope
Allosteric activation of membrane-bound glutamate receptors using coordination chemistry within living cells
NeuroscienceJun 27 2016Nature Chemistry

Shigeki Kiyonaka*First author, Corresponding author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan

Itaru Hamachi*Last author, Corresponding author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan

Inverted Microscopes
Micro–adhesion rings surrounding TCR microclusters are essential for T cell activation
Cancer & ImmunologyJun 27 2016The Journal of Experimental Medicine

Akiko Hashimoto-Tane*First author, Corresponding author

Laboratory for Cell Signaling, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan

Takashi Saito*Last author, Corresponding author

Laboratory for Cell Signaling, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan 

TIRF Objectives
p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress
Stem CellsJun 23 2016Cell Stem Cell

Daiki Karigane*First author

Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan

Keiyo Takubo*Last author, Corresponding author

Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan

Confocal Laser Scanning Microscope
Autophagosome–lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome
Cell BiologyJun 23 2016The EMBO Journal

Junya Hasegawa*First author

Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences Osaka University, Osaka, Japan

Tamotsu Yoshimori*Last author, Corresponding author

Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences Osaka University, Osaka, Japan

Confocal Laser Scanning Microscope
Moss Chloroplasts are Surrounded by a Peptidoglycan Wall Containing D-Amino Acids
Plant & Animal ScienceJun 20 2016The Plant Cell

Takayuki Hirano* First author

Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555, Japan

Hiroyoshi Takano*Last author, Corresponding author

Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555, Japan

Confocal Laser Scanning Microscope
Developmental regression of hyaloid vasculature is triggered by neurons
Biomedical ResearchJun 20 2016The Journal of Experimental Medicine

Yusuke Yoshikawa* First author

Department of Vascular Biology, The Sakaguchi Laboratory, School of Medicine, Keio University, Shinjuku-ku, Tokyo 160-8582, Japan

Toru Yamada*Co-first author

Department of Vascular Biology, The Sakaguchi Laboratory, School of Medicine, Keio University, Shinjuku-ku, Tokyo 160-8582, Japan
Yoshiaki Kubota*Last author, Corresponding author

Department of Vascular Biology, The Sakaguchi Laboratory, School of Medicine, Keio University, Shinjuku-ku, Tokyo 160-8582, Japan 

Confocal Laser Scanning Microscope
Sperm Affects Head Sensory Neuron in Temperature Tolerance of Caenorhabditis elegans
NeuroscienceJun 16 2016Cell Reports

Satoru Sonoda* First author

Laboratory of Molecular and Cellular Regulation, Faculty of Science and Engineering, and Institute for Integrative Neurobiology, Konan University, 8-9-1 Okamoto, Higashinada-ku, Kobe 658-8501, Japan

Akane Ohta*Corresponding author

Laboratory of Molecular and Cellular Regulation, Faculty of Science and Engineering, and Institute for Integrative Neurobiology, Konan University, 8-9-1 Okamoto, Higashinada-ku, Kobe 658-8501, Japan

Atsushi Kuhara*Last author, Corresponding author

Laboratory of Molecular and Cellular Regulation, Faculty of Science and Engineering, and Institute for Integrative Neurobiology, Konan University, 8-9-1 Okamoto, Higashinada-ku, Kobe 658-8501, Japan

Confocal Laser Scanning Microscope
Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1
Cell BiologyJun 13 2016Nature Communications

Shigeru Matsumura*First author, Corresponding author

Department of Cell Biology, Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan

Fumiko Toyoshima*Last author

Department of Cell Biology, Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan

Z Drift Compensator
Phytochrome signaling is mediated by PHYTOCHROME INTERACTING FACTOR in the liverwort Marchantia polymorpha
Plant & Animal ScienceJun 01 2016The Plant Cell

Keisuke Inoue* First author

Graduate School of Biostudies, Kyoto University, Kyoto, 606-8502, Japan

Takayuki Kohchi*Last author, Corresponding author

Graduate School of Biostudies, Kyoto University, Kyoto, 606-8502, Japan

Confocal Laser Scanning Microscope
Olfactory receptor for prostaglandin F2α mediates male fish courtship behavior
NeuroscienceMay 30 2016Nature Neuroscience

Yoichi Yabuki* First author

RIKEN Brain Science Institute, Saitama, Japan

Yoshihiro Yoshihara*Last author, Corresponding author

RIKEN Brain Science Institute, Saitama, Japan

Confocal Laser Scanning Microscope
Phosphorylation‐dependent Akt–Inversin interaction at the basal body of primary cilia
Cell BiologyMay 23 2016The EMBO Journal

Futoshi Suizu* First author

Division of Cancer Biology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

Masayuki Noguchi*Last author, Corresponding author

Division of Cancer Biology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

Confocal Laser Scanning Microscope
Cyclic Nucleotide Control of Microtubule Dynamics for Axon Guidance
NeuroscienceMay 18 2016The Journal of Neuroscience

Hiroki Akiyama* First author

Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan

Hiroyuki Kamiguchi*Last author, Corresponding author
Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan 

TIRF Objectives
Vascular Cell Induction Culture System Using Arabidopsis Leaves (VISUAL) Reveals the Sequential Differentiation of Sieve Element-like Cells
Plant & Animal ScienceMay 18 2016The Plant Cell

Yuki Kondo* First author, Corresponding author

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Hiroo Fukuda*Last author, Corresponding author

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Confocal Laser Scanning Microscope
Transient neuronal coactivations embedded in globally propagating waves underlie resting-state functional connectivity
NeuroscienceMay 16 2016PNAS

Teppei Matsui* First author

Department of Physiology, The University of Tokyo School of Medicine, Tokyo 113-0033, Japan

Kenichi Ohki*Last author, Corresponding author

Department of Physiology, The University of Tokyo School of Medicine, Tokyo 113-0033, Japan

Research Macro Zoom Microscope
F1-ATPase conformational cycle from simultaneous single-molecule FRET and rotation measurements
BioimagingMay 10 2016PNAS

Mitsuhiro Sugawa* First author

Department of Physics, Faculty of Science, Gakushuin University, Tokyo 171-8588, Japan

Takayuki Nishizaka*Last author, Corresponding author

Department of Physics, Faculty of Science, Gakushuin University, Tokyo 171-8588, Japan

TIRF Objectives
Regulation of podocalyxin trafficking by Rab small GTPases in 2D and 3D epithelial cell cultures
Cell BiologyMay 02 2016The Journal of Cell Biology

Paulina S. Mrozowska* First author

Laboratory of Membrane Trafficking Mechanisms, Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi 980-8578, Japan

Mitsunori Fukuda*Last author, Corresponding author

Laboratory of Membrane Trafficking Mechanisms, Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi 980-8578, Japan

Confocal Laser Scanning Microscope

Sorry, this page is not
available in your country.

This site uses cookies to enhance performance, analyze traffic, and for ads measurement purposes. If you do not change your web settings, cookies will continue to be used on this website. To learn more about how we use cookies on this website, and how you can restrict our use of cookies, please review our Cookie Policy.

OK